Sains Malaysiana 44(8)(2015): 11251128

 

The Chemical Constituents of Ellipeia cuneifolia and Their Antibacterial Activity

(Komposisi Kimia Ellipeia cuneifolia dan Aktiviti Antibakterianya)

 

HASLIZA YUSOF1, LAILY B. DIN1, WAN A. YAACOB1*, NAZLINA IBRAHIM2, BOHARI M. YAMIN1 & A. LATIFF3

 

1School of Chemical Sciences and Food Technology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E. Malaysia

 

2School of Biosciences and Biotechnology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E. Malaysia

 

3School of Environmental and Natural Resource Sciences, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E., Malaysia

 

Received: 6 October 2014/Accepted: 9 April 2015

 

ABSTRACT

Chromatographic purification of chloroform extract of the twigs of Ellipeia cuneifolia has led to the discovery of three compounds comprising of 2,4-dihydroxy-4,6-dimethoxychalcone; tepanone; and O-methylmoschatoline. Structures of the compounds were established by interpreting their spectral data and by comparing them with those of the literature. Two of them showed antibacterial activities.

 

Keywords: Annonaceae; antibacterial activity; chalcone; Ellipeia cuneifolia; oxoaporphine; chalcone; twig

 

ABSTRAK

Penulenan kromatografi terhadap ekstrak kloroform ranting Ellipeia cuneifolia membawa kepada penemuan 3 sebatian iaitu 2,4-dihidroksi-4,6-dimetoksikalkon; tepanon; dan O-metilmoskatolina. Struktur sebatian ini telah ditentukan dengan mentafsirkan data spektrum dan membandingkannya dengan data spektrum daripada penerbitan. Dua daripadanya menunjukkan aktiviti antibakteria.

 

Kata kunci: Aktiviti antibakteria; Annonaceae; Ellipeia cuneifolia; kalkon; oksoaporfina; ranting; retrokalkon

REFERENCES

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Zawawi, N.K.N.A., Ahmat, N., Ahmad, R., Jaafar, F.M. & Ghani, N.A. 2012. Oxoaporphine alkaloids and flavonols from Xylopia ferruginea (Annonaceae). Biochemical Systematics and Ecology 43: 7-9.

 

 

*Corresponding author; email: wanyaa@ukm.edu.my

 

 

 

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