Sains Malaysiana 44(8)(2015): 1125–1128

 

The Chemical Constituents of Ellipeia cuneifolia and Their Antibacterial Activity

(Komposisi Kimia Ellipeia cuneifolia dan Aktiviti Antibakterianya)

 

HASLIZA YUSOF1, LAILY B. DIN1, WAN A. YAACOB1*, NAZLINA IBRAHIM2, BOHARI M. YAMIN1 & A. LATIFF3

 

1School of Chemical Sciences and Food Technology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E. Malaysia

 

2School of Biosciences and Biotechnology, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E. Malaysia

 

3School of Environmental and Natural Resource Sciences, Faculty of Science and Technology

Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor D.E., Malaysia

 

Received: 6 October 2014/Accepted: 9 April 2015

 

ABSTRACT

Chromatographic purification of chloroform extract of the twigs of Ellipeia cuneifolia has led to the discovery of three compounds comprising of 2’,4’-dihydroxy-4,6’-dimethoxychalcone; tepanone; and O-methylmoschatoline. Structures of the compounds were established by interpreting their spectral data and by comparing them with those of the literature. Two of them showed antibacterial activities.

 

Keywords: Annonaceae; antibacterial activity; chalcone; Ellipeia cuneifolia; oxoaporphine; chalcone; twig

 

ABSTRAK

Penulenan kromatografi terhadap ekstrak kloroform ranting Ellipeia cuneifolia membawa kepada penemuan 3 sebatian iaitu 2’,4’-dihidroksi-4,6’-dimetoksikalkon; tepanon; dan O-metilmoskatolina. Struktur sebatian ini telah ditentukan dengan mentafsirkan data spektrum dan membandingkannya dengan data spektrum daripada penerbitan. Dua daripadanya menunjukkan aktiviti antibakteria.

 

Kata kunci:  Aktiviti antibakteria; Annonaceae; Ellipeia cuneifolia; kalkon; oksoaporfina; ranting; retrokalkon

REFERENCES

Colegate, S.M., Din, L.B., Ghisalberti, E.L. & Latiff, A. 1992. Tepanone, a retrochalcone from Ellipeia cuneifolia. Phytochemistry 31: 2123-2126.

Kessler, P.J.A. 1993. Annonaceae. In The Families and Genera of Vascular Plants. Volume II. Flowering Plants. Dicotyledons: MagnoliidHamamelid and Caryophyllid Families, edited by Kubitzki, K., Rohwer, J.G. & Bittrich, V. Berlin: Springer- Verlag. pp. 93-129.

Ridley, H.N. 1922. The flora of the Malay Peninsula. Vol II. Reprinted 1967. London: L. Reeve & Co.

Seidel, V., Bailleul, F. & Waterman, P.G. 2000. (Rel)- 1β,2α-di-(2,4-dihydroxy-6-methoxybenzoyl)-3β,4α-di-(4- methoxyphenyl)-cyclobutane and other flavonoids from the aerial parts of Goniothalamus gardneri and Goniothalamus thwaitesii. Phytochemistry 55: 439-446.

Sinclair, J. 1955. A revision of the Malayan Annonaceae. Gardens’ Bulletin Singapore 14(2): 149-516.

Wijeratne, E.M.K., Hatanaka, Y., Kikuchi, T., Tezuka, Y. & Gunatilaka, A.A.L. 1996. A dioxoapophine and other alkaloids of two Annonaceous plants of Sri Lanka. Phytochemistry 42: 1703-1706.

Zawawi, N.K.N.A., Ahmat, N., Ahmad, R., Jaafar, F.M. & Ghani, N.A. 2012. Oxoaporphine alkaloids and flavonols from Xylopia ferruginea (Annonaceae). Biochemical Systematics and Ecology 43: 7-9.

 

 

*Corresponding author; email: wanyaa@ukm.edu.my

 

 

 

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