Sains Malaysiana 46(9)(2017): 1625–1633

http://dx.doi.org/10.17576/jsm-2017-4609-35

 

Pengehadan Kalori, Fungsi Kognitif dan Penuaan: Peranan terhadap Sistem Biologi

(Caloric Restriction, Cognitive Function and Aging: Roles towards Biologic System)

 

MERAMAT, A.¹, RAJAB, N.F.², SHAHAR, S.³ & SHARIF, R.^1*

 

¹Program Sains Pemakanan, Pusat Pengajian Sains Jagaan Kesihatan, Fakulti Sains Kesihatan

Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur,

Wilayah Persekutuan, Malaysia

 

²Program Sains Bioperubatan, Pusat Sains Diagnostik dan Kesihatan Gunaan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur, Wilayah Persekutuan, Malaysia

 

³Program Dietetik, Pusat Pengajian Sains Jagaan Kesihatan, Fakulti Sains Kesihatan

Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur,

Wilayah Persekutuan, Malaysia

 

Received: 20 December 2016/Accepted: 20 April 2017

 

 

ABSTRAK

Prevalens gangguan kognitif ringan (MCI) di Malaysia mencecah 68% pada tahun 2016. Pelbagai kaedah dijalankan bagi memastikan kelestarian tahap kesihatan warga tua termasuk melalui nutrisi, gaya hidup dan persekitaran. Pengehadan kalori dibuktikan mampu untuk menurunkan kadar mortaliti dan morbiditi warga tua serta memelihara tahap kesihatan warga tua supaya dapat membantu dalam meningkatkan kualiti hidup golongan tersebut. Pengehadan kalori juga merupakan salah satu kaedah yang lebih mudah dan berkesan dalam membantu meningkatkan ingatan dan memelihara kesihatan golongan tersebut. Ia juga membantu mengurangkan kadar inflamasi dan mencantas tindakan radikal bebas yang hadir di dalam sistem tubuh akibat daripada proses penuaan dan faktor persekitaran. Keadaan ini menyediakan tubuh badan yang lebih rentan terhadap kerosakan DNA dan serangan toksin daripada penyakit kronik, pemakanan dan persekitaran. Oleh itu, kajian ini memberikan konsep yang lebih jelas terhadap implikasi pengehadan kalori dalam memelihara fungsi kognitif.

 

Kata kunci: Fungsi kognitif; pengehadan kalori; warga tua

 

ABSTRACT

The prevalence of mild cognitive impairment (MCI) in Malaysia reached 68% in 2016. Various methods including nutrition, lifestyle and environment are carried out to ensure the sustainability of the health of older adults. Caloric restriction has been discovered to lower mortality and morbidity rate and preserving the health of older adult in order to improve their quality of life. Caloric restriction is also one of the methods that is easier and effective in order to improve the memory and maintaining the health in this group. It also aids in reducing inflammation rate and pruning the action of free radicals present in the body system as a result of the aging process and environmental factors. This situation provides the body less prone to DNA damage and toxin attacks from chronic diseases, nutrition and environment. Therefore, the literature review will provide a clearer concept on implication of calorie restriction in maintaining cognitive function.

 

Keywords: Caloric restriction; cognitive function; older adult

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*Corresponding author; email: razinah@ukm.edu.my