Sains Malaysiana 46(9)(2017): 1625–1633
http://dx.doi.org/10.17576/jsm-2017-4609-35
Pengehadan Kalori, Fungsi Kognitif dan Penuaan: Peranan terhadap Sistem Biologi
(Caloric Restriction, Cognitive Function and Aging: Roles
towards Biologic System)
MERAMAT, A.1, RAJAB, N.F.2, SHAHAR, S.3 & SHARIF, R.1*
1Program Sains Pemakanan, Pusat Pengajian Sains Jagaan Kesihatan, Fakulti Sains Kesihatan
Universiti Kebangsaan Malaysia, Jalan Raja
Muda Abd Aziz, 50300 Kuala Lumpur,
Wilayah
Persekutuan, Malaysia
2Program Sains Bioperubatan, Pusat Sains Diagnostik dan Kesihatan Gunaan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300
Kuala Lumpur, Wilayah Persekutuan, Malaysia
3Program Dietetik, Pusat Pengajian Sains Jagaan Kesihatan, Fakulti Sains Kesihatan
Universiti Kebangsaan Malaysia, Jalan Raja
Muda Abd Aziz, 50300 Kuala Lumpur,
Wilayah
Persekutuan, Malaysia
Received:
20 December 2016/Accepted: 20 April 2017
ABSTRAK
Prevalens gangguan kognitif
ringan (MCI) di Malaysia mencecah 68% pada tahun 2016. Pelbagai kaedah dijalankan bagi memastikan kelestarian tahap kesihatan warga tua termasuk
melalui nutrisi,
gaya hidup
dan persekitaran.
Pengehadan kalori dibuktikan mampu untuk menurunkan kadar mortaliti
dan morbiditi
warga tua serta
memelihara tahap
kesihatan warga tua supaya dapat
membantu dalam
meningkatkan kualiti hidup golongan tersebut. Pengehadan kalori juga merupakan
salah satu
kaedah yang lebih mudah dan berkesan dalam
membantu meningkatkan ingatan dan memelihara kesihatan golongan tersebut. Ia
juga membantu mengurangkan
kadar inflamasi dan mencantas tindakan
radikal bebas
yang hadir di dalam sistem tubuh akibat
daripada proses penuaan
dan faktor persekitaran.
Keadaan
ini menyediakan tubuh badan yang lebih rentan terhadap
kerosakan DNA dan
serangan toksin
daripada penyakit kronik, pemakanan dan persekitaran. Oleh itu, kajian ini
memberikan konsep
yang lebih jelas terhadap
implikasi pengehadan
kalori dalam memelihara
fungsi kognitif.
Kata kunci: Fungsi kognitif; pengehadan kalori; warga tua
ABSTRACT
The prevalence of
mild cognitive impairment (MCI) in Malaysia reached 68% in 2016.
Various methods including nutrition, lifestyle and environment are carried out
to ensure the sustainability of the health of older adults. Caloric restriction
has been discovered to lower mortality and morbidity rate and preserving the
health of older adult in order to improve their quality of life. Caloric
restriction is also one of the methods that is easier
and effective in order to improve the memory and maintaining the health in this
group. It also aids in reducing inflammation rate and pruning the action of
free radicals present in the body system as a result of the aging process and
environmental factors. This situation provides the body less prone to DNA damage
and toxin attacks from chronic diseases, nutrition and environment. Therefore,
the literature review will provide a clearer concept on implication of calorie
restriction in maintaining cognitive function.
Keywords: Caloric restriction; cognitive function; older adult
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