Sains Malaysiana 48(6)(2019): 1259–1265

http://dx.doi.org/10.17576/jsm-2019-4806-13

 

Refractive Index and Sensing of Glucose Molarities determined using Au-Cr K-SPR at 670/785 nm Wavelength

(Indeks Biasan dan Pengesanan Kemolaran Glukosa melalui Au-Cr K-SPR pada Panjang Gelombang 670/785 nm)

 

P. SUSTHITHA MENON1*, BUDI MULYANTI2, NUR AKMAR JAMIL1, CHANDRA WULANDARI3, HARBI SETYO NUGROHO3, GAN SIEW MEI1, NOOR FAIZAH ZAINUL ABIDIN1, LILIK HASANAH3, ROER EKA PAWINANTO2 & DILLA DURYHA BERHANUDDIN1

 

1Institute of Microengineering and Nanoelectronics (IMEN), Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor Darul Ehsan, Malaysia

 

2Department of Electrical Engineering Education, Universitas Pendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia

 

3Department of Physics Education, Universitas Pendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia

 

Diserahkan: 2 Januari 2019/Diterima: 28 Februari 2019

 

ABSTRACT

In this paper, we determine the optical refractive indices of different molarities of glucose using nano-laminated gold/chromium (Au-Cr) thin film via Kretschmann-based Surface Plasmon Resonance (K-SPR) sensing with angular interrogation. The nano-laminated Au-Cr K-SPR sensor detects the glucose presence in low- and high-concentration of 4-12 mmol/L and 55-277 mmol/L, respectively, under the exposure of 670 nm and 785 nm optical wavelengths. The experimental results showed that the minimum limit of detection (LOD) of Au-Cr K-SPR is 4 mmol/L and the glucose sensor sensitivities are in average of 3.41 o/M and 2.73o/M at 670 nm and 785 nm optical wavelength, respectively. Stable sensitivity for each concentration also shown from the sensorgram results, indicates the stable performance of nano-laminated Au-Cr SPR sensor to detect glucose in the range from mmol/L up to dmol/L. Values of refractive indices for glucose molarities obtained are 1.33187 (4 mmol/L) and 1.3191 (4 mmol/L) at 670 and 785 nm wavelength, respectively. These RI values are beneficial for numerical simulation of glucose sensors using nano-laminated Au-Cr thin films which have been reported for the first time. The sensor can be eventually deployed in integrated photonic sensing devices comprising of multiple analyte detection for lab-on-chip (LoC) and point-of care (PoC) applications.

 

Keywords: Angular interrogation; glucose sensor; gold/chromium; Kretschmann; nano-laminated; refractive index; surface plasmon resonance

 

ABSTRAK

Dalam kajian ini, indeks biasan optik daripada kemolaran glukosa yang berbeza ditentukan dengan menggunakan filem nipis nano emas/kromium (Au-Cr) melalui sensor resonan plasmon permukaan berasaskan konfigurasi Kretschmann (K-SPR) dengan interogasi sudut. Sensor Au-Cr K-SPR berlapis nano mengesan kehadiran glukosa dalam kepekatan rendah dan tinggi iaitu 4-12 mmol/L dan 55-277 mmol/L masing-masing di bawah pendedahan panjang gelombang optik 670 nm dan 785 nm. Keputusan uji kaji menunjukkan bahawa had minimum pengesanan (LOD) Au-Cr K-SPR adalah 4 mmol/L dan kepekaan sensor glukosa adalah secara purata sebanyak 3.41°/M dan 2.73°/M, masing-masing pada panjang gelombang 670 nm dan 785 nm. Pengesanan yang stabil daripada sensorgram untuk setiap kepekatan glukosa menunjukkan prestasi sensor Au-Cr SPR nano-lamina untuk mengesan glukosa dalam lingkungan dari mmol/L sehingga dmol/L. Nilai indeks biasan (RI) untuk kemolaran glukosa yang diperoleh ialah 1.33187 (4 mmol/L) dan 1.3191 (4 mmol/L) pada panjang gelombang 670 dan 785 nm. Nilai RI ini bermanfaat untuk simulasi berangka sensor glukosa menggunakan filem tipis nano-lamina Au-Cr yang dilaporkan buat pertama kali. Sensor ini akhirnya boleh digunakan dalam peranti terintegrasi fotonik yang bersepadu yang terdiri daripada pelbagai pengesanan analit untuk aplikasi makmal-atas-cip (LoC) dan point-of care (PoC).

 

Kata kunci: Emas/kromium; indeks biasan; interograsi sudut; konfigurasi Kretschmann; nano-lamina; resonan plasmon permukaan; sensor glukosa

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*Pengarang untuk surat-menyurat; email: susi@ukm.edu.my

 

 

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