Sains Malaysiana 49(3)(2020): 653-660

http://dx.doi.org/10.17576/jsm-2020-4903-20

 

The Effect of Different Concentrations of Calcium Silicate-Maghemite Coating towards Magnetic Behavior and Bioactivity

(Kesan Kepekatan Berbeza Salutan Kalsium Silikat-Magemit kepada Tingkah Laku Magnet dan Aktiviti Bionya)

 

NOR HAZIRAH MOHD AKHIRUDIN, ROSLINDA SHAMSUDIN & NORINSAN KAMIL OTHMAN*

 

School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor Darul Ehsan, Malaysia

 

Diserahkan: 10 September 2019/Diterima: 5 Disember 2019

 

ABSTRACT

In this study, maghemite (γ-Fe2O3) as magnetic nanoparticles (MNPs) material was coated by ceramic materials, calcium silicate (CaSiO3) with different concentrations to suit the medical treatment needed. Different concentration was studied to assess the optimal parameter and ability to maintain post-coated superparamagnetic properties of γ-Fe2O3.  Concentration of CaSiO3 coated on γ-Fe2O3 was prepared with 3 parameters, 97:3, 95:5, and 93:7% w/w, respectively. Magnetic properties of CaSiO3-γ-Fe2O3 were characterized by VSM proceeded with a bioactive study analyzed with FESEM and FTIR after simulated body fluid immersion for 5 days at 37±1ºC. CaSiO3-γ-Fe2O3 with concentration 95:5% w/w exhibit the highest magnetization makes it the most optimum with the average coercivity is 1.6G. FESEM analysis illustrates that the existence of the apatite layer after 5 days of simulated body fluid (SBF) immersion on CaSiO3-γ-Fe2O3 coating sample, which confirmed the bioactive properties. Therefore, CaSiO3-γ-Fe2O3 concentration at ratio 95:5% w/w can be a promising new biomaterial candidate to be applied in the medical field.

 

Keywords: Bioactive; calcium silicate coating; maghemite; superparamagnetic

 

ABSTRAK

Dalam kajian ini, magemit (γ-Fe2O3) sebagai bahan nanozarah magnetik (MNPs) disalut oleh bahan seramik iaitu kalsium silikat (CaSiO3) dengan kepekatan yang berbeza untuk memenuhi keperluan rawatan perubatan. Kepekatan yang berbeza dikaji untuk menentukan parameter yang ideal dan keupayaan untuk mengekalkan sifat superparamagnetik yang dimiliki oleh γ-Fe2O3 selepas proses salutan. Kepekatan CaSiO3 menyalut kepada γ-Fe2O3 disediakan dengan 3 parameter yang berbeza, 97:3% w/w, 95:5% w/w dan 93:7% w/w. Sifat magnetik CaSiO3-γ-Fe2O3 dicirikan oleh VSM kemudiannya diteruskan dengan kajian sifat bioaktif yang dianalisis menggunakan FESEM dan FTIR selepas direndamkan ke dalam larutan simulasi badan (SBF) selama hari pada 37 ± 1ºC. CaSiO3-γ-Fe2O3 dengan kepekatan 95:5% w/w menunjukkan nilai magnetisasi tertinggi menjadikannya parameter paling optimum dengan purata koersiviti ialah 1.6G. Analisis FESEM menunjukkan kehadiran lapisan apatit selepas 5 hari rendaman SBF pada sampel CaSiO3-γ-Fe2O3 mengesahkan sifat bioaktif yang dimiliki. Oleh itu, kepekatan CaSiO3-γ-Fe2O3 pada nisbah 95:5% w/w mempunyai potensi untuk dijadikan calon biobahan yang baru untuk diaplikasikan dalam bidang perubatan.

 

Kata kunci: Bioaktif; magemit; salutan kalsium silikat; superparamagnetik

 

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*Pengarang untuk surat-menyurat; email: insan@ukm.edu.my

 

 

 

 

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