Malaysian Journal of Analytical Sciences Vol 21 No 6 (2017): 1327 - 1334

MOLECULARLY IMPRINTED POLYMER-COATED QUARTZ CRYSTAL MICROBALANCE FOR DETECTION OF PARATHION

(Polimer Molekul Tercetak Saduran Kristal Kuarza Penimbang Mikro bagi Penentuan Parathion)

Xiamin Cheng^1,
3, Qihui Zhang², Sam Fong Yau Li^{1, 2}*, Bin Liu³

¹NUS Environmental Research Institute,

5A Engineering Drive 1, T-Lab Building, 117411, Singapore

²Department of Chemistry,

National University of Singapore, 3 Science Drive 3, 117543, Singapore

³Department of Chemical & Biomolecular Engineering,

National University of Singapore, Engineering Drive 4, Blk E5 #02-17, 117585, Singapore

*Corresponding author: chmlifys@nus.edu.sg

Received: 7 November 2016; Accepted: 18 September 2017

Abstract

Organophosphorus compounds (OPs) as important components of insecticides, pesticides, and chemical threat agents (CTA), have become more and more serious threats to the environment. Real-time monitoring of the threats is an urgent demand for environmental safety. The molecular imprinting polymer (MIP) technique is an attractive method for the generation of polymer-based molecular “memory” for a present target or group of target molecules. In this work, we integrate a novel MIP with quartz crystal microbalance (QCM) to build a simple sensor to selectively monitor OP in water samples in real-time. The MIP system was built up by polymerization of methacryalic acid (MAA) with divinylbenzene (DVB), initiated with 2,2’-azobis(2-methylpropionitrile) (AIBN) in presence of target. The polymer was characterized with FT-IR. Using parathion as a representative template, the MIP was coated on QCM by casting a semi-polymerized solution. The sensor could detect parathion in wide range from 290 ppb to 29 ppm. This sensor is stable, easy to prepare which can be reused and has the potential to be applied other analytes, which are threats to the environment.

Keywords: organophosphorus compounds, molecular imprinting polymer, quartz crystal microbalance, parathion

Abstrak

Sebatian organofosforus (OPs) adalah kompenen penting bagi racun serangga, racun mahkluk perosak dan agen kimia berbahaya yang telah menjadi ancaman kepada alam sekitar. Pemantauan terhadap ancaman ini telah meningkat berdasarkan kepada keselamatan alam sekitar. Teknik polimer molekul tercetak (MIP) adalah kaedah yang menarik molekul berasaskan polimer yang mempunyai sasaran terhadap molekul tertentu. Dalam kajian ini, MIP tulen bersama penimbang mikro kristal kuarza (QCM) telah disepadu untuk menghasilkan sensor mudah bagi pemantauan terpilih kehadiran OP di dalam sampel air bagi siutuasi sebenar. Sistem MIP telah dibangunkan berdasarkan pempolimeran asid metakrialik (MAA) dan divinilbenzena (DVD), dimulakan dengan kehadiran 2,2’-azobis(2-metilpropionitril)(AIBN) sebagai sasaran. Polimer telah dicirikan menggunakan FT-IR. Menggunakan parathion sebagai templat, MIP disadur ke atas QCM melalui teknik saduran larutan separa polimer. Sensor berupaya mengesan parathio pada julat yang besar dari 290 ppb hingga 29 ppm. Sensor ini adalah stabil, mudah disediakan, dimana boleh diguna semula dan berpotensi untuk diaplikasi terhadap analit lain yang mengancam alam sekitar.

Kata kunci: sebatian organofosforus, polimer molekul tercetak, penimbang mikro kristal kuarza, parathion

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