Malaysian Journal of Analytical Sciences Vol 21 No 6 (2017): 1373 - 1379

SURFACE PLASMON RESONANCE SENSOR FOR DETECTION OF PARATHION METHYL IN WATER

(Sensor Permukaan Plasmon Resonan bagi Pengesanan Parathion Metil di dalam Air)

Baisheng Chen¹, Douglas Chiang Yon Chong¹, Xiamin Cheng^{2, 3}, Bin Liu³, Sam Fong Yau Li^{1, 2}*

¹Department of Chemistry,

National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore

²NUS Environmental Research Institute (NERI),

#02-01, T-Lab Building (TL), 5A Engineering Drive 1, Singapore 117411, Singapore

³Department of Chemical & Biomolecular Engineering,

National University of Singapore, 4 Engineering Drive 4, Block E5 #02-17, 117585, Singapore

*Corresponding author: chmlifys@nus.edu.sg

Received: 7 November 2016; Accepted: 18 September 2017

Abstract

A surface plasmon resonance (SPR) sensor based on molecularly imprinted polymer (MIP) was developed for fast detection of chemical threat agents (CTAs) in water. A portable SPR platform provided a very compact-size (L*W*H of 8.5*4.5*4.5 inch) system and the SPR sensor chip was fabricated by a facile process with an inexpensive coating of silver as the SPR material, making possible the sensor chip as a disposal sensor. Using methyl parathion as the simulant of CTA, the developed SPR sensor with the recognition site showed apparent SPR signal than Non-imprinted polymer (NIP) counterpart, suggesting the excellent recognition of the targeted molecules. It also provided a fast responding within 5 minutes with the limit of detection of sub-ppm level.

Keywords: molecularly imprinted polymer, surface plasmon resonance, organophosphorus pesticide, chemical threat agents

Abstrak

Sensor permukaan plasmon resonans (SPR) berdasarkan polimer molekul tercetak (MIP) telah dibangunkan bagi pengesanan pantas ejen ancaman kimia (CTAs) di dalam air. Sistem platform SPR mudah alih bersaiz padat disediakan (L*W*H 8.5*4.5*4.5 inci) dan cip sensor SPR telah diubahsuai melalui proses mudah dengan salutan murah perak sebagai bahan SPR, menjadikan cip sensor sebagai sensor mudah dilupuskan. Menggunakan parathion metil sebagai sasaran CTA, sensor SPR yang telah dibangunkan dengan bahagian yang dikenalpasti itu menunjukkan isyarat jelas daripada SPR berbanding polimer tak tercetak (NIP), menunjukkan pengenalpastian baik bagi molekul yang disasarkan. Ia juga memberi respons yang cepat dalam masa 5 minit dengan had pengesanan pada aras sub-ppm.

Kata kunci: polimer molekul tercetak, permukaan plasmon resonans, racun perosak organofosforus, agen kimia berbahaya

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