Malaysian Journal of Analytical Sciences Vol 21 No 6 (2017): 1409 - 1416

STUDY ON THE EFFECT OF OIL PHASE AND CO-SURFACTANT ON MICROEMULSION SYSTEMS

(Kajian Kesan Fasa Minyak dan Ko-Surfaktan Terhadap Sistem Mikroemulsi)

Muhammad Asri Abd Sisak¹, Rusli Daik^1,2, Suria Ramli^1,2*

¹School of Chemical Sciences and Food Technology

²Polymer Research Center

Faculty of Science and Technology,

Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia

*Corresponding author: su_ramli@ukm.edu.my

Received: 28 September 2016; Accepted: 6 March 2017

Abstract

The purpose of the present study was to investigate the effect of different oil and chain lengths of co-surfactant on microemulsion region. Oleic acid and isopropyl myristate were used as the oil phase, transcutol, polyethylene glycol 400 (PEG 400) and propylene glycol as co-surfactant and Brij 97 as a surfactant. From the ternary phase diagrams, isopropyl myristate based system is more feasible oil phase to formulate microemulsion compared to oleic acid based system. Moreover, transcutol (medium chain length) is the most suitable co-surfactant to blend with a single-chain surfactant, Brij 97 in order to have a high stability and a large area of microemulsion region.

Keywords: microemulsion, oleic acid, isopropyl myristate, transcutol, propylene glycol

Abstrak

Kajian ini bertujuan untuk mengkaji kesan minyak yang berbeza dan panjang rantai ko-surfaktan terhadap rantau mikroemulsi. Asid oleik dan isopropil miristat telah digunakan sebagai fasa minyak, transcutol, polietilena glikol 400 (PEG 400) dan propilena glikol sebagai ko-surfaktan dan Brij 97 sebagai surfaktan. Rajah fasa tenari, sistem berasaskan isopropil miristat adalah fasa minyak yang lebih sesuai untuk membentuk mikroemulsi berbanding sistem berasaskan asid oleik. Selain itu, transcutol yang berantai sederhana panjang adalah ko-surfaktan yang sesuai untuk diformulasikan bersama surfaktan rantai tunggal, Brij 97 yang memberikan rantau kawasan mikroemulsi yang besar dengan kestabilan yang tinggi.

Kata kunci: mikroemulsi, asid oleik, isopropil miristat, transcutol, propilena glikol

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