Sains Malaysiana 48(12)(2019): 2693–2699

http://dx.doi.org/10.17576/jsm-2019-4812-10

 

Clinical and Pathological Evaluation of Benign Skin Lesions

(Penilaian Klinikal dan Patologi Lesi Kulit Benigna)

 

SABAHATTIN DESTEK1* & VAHIT ONUR GUL2

 

1Department of General Surgery, Bezmialem Vakıf University School of Medicine, 34093 Fatih, Istanbul, Turkey

 

2Department of General Surgery, Gulhane Education and Research Hospital, 06010 Etlik, Ankara, Turkey

 

Received: 13 February 2019/Accepted: 23 September 2019

 

ABSTRACT

Skin lesions are commonly benign in nature. The present study aims to evaluate the prevalence and clinicopathological characteristics of a large series of benign skin lesions (BSLs) excised in our clinic. Patients with skin lesions who underwent total excisional biopsy at the general surgery clinic between 2012 and 2016 were reviewed. A total of 551 patients with BSLs were included in the study. Of these, 43.7% were females and 56.7% were males. The age range was between 2 and 98 years with a mean of 39.7 years. The most commonly occurring group of BSLs was of the appendageal tumors (33.3%), and this finding was statistically significant. The most common keratinocytic BSL (13.6%) was verruca vulgaris. In the present study, various types of BSLs and their occurrences were evaluated. Benign skin tumors can turn into malignant types. A biopsy should be performed to establish the exact diagnosis. We performed an excisional biopsy to confirm the diagnosis.

Keywords: Benign skin lesions; clinicopathological examination; excisional biopsy

 

ABSTRAK

Lesi kulit adalah perkara biasa dan kebanyakannya lesi jinak. Tujuan kajian ini adalah untuk menilai kelaziman dan ciri klinikopatologi siri besar lesi kulit benigna yang dikeluarkan di klinik kami. Pesakit yang mengalami lesi kulit dikaji semula, yang menjalani jumlah biopsi ekslusif dalam klinik pembedahan umum antara 2012 dan 2016. Sejumlah 551 pesakit dengan lesi kulit benigna termasuk dalam kajian ini. Daripada pesakit ini, 43.7% adalah wanita dan 56.7% adalah lelaki. Julat umur adalah antara 2 dan 98 tahun dengan purata 39.7 tahun. Kumpulan yang paling biasa (33.3%) lesi kulit jinak adalah tumor lampiran dan penemuan ini secara statistik secara signifikan. Lesi kulit yang paling biasa (13.6%) adalah verruca vulgaris. Dalam kajian ini, pelbagai jenis lesi kulit benigna dan frekuensi relatifnya dinilai. Tumor kulit benigna boleh berubah menjadi jenis malignan. Biopsi perlu diambil untuk menentukan diagnosis yang tepat. Kami melakukan biopsi pengecualian untuk diagnosis.

Kata kunci: Biopsi eksisi; lesi kulit benigna; pemeriksaan klinikopatologi

RUJUKAN

Bas, Y., Kalkan, G., Seckin, H.Y., Takcı, Z., Sahin, S. & Demir, A.K. 2014. Analysis of dermatologic problems in geriatric patients. Turkish Journal of Dermatology 8(4): 206-209.

Bertanha, F., Nelumba, E.J., Freiberg, A.K., Samorano, L.P. & Neto, F.C. 2016. Profile of patients admitted to a triage dermatology clinic at a tertiary hospital in São Paulo, Brazil. Anais brasileiros de dermatologia 91(3): 318-325.

Choi, S.H., Kim, K.H. & Song, K.H. 2016. Clinical features of cutaneous premalignant lesions in Busan City and the Eastern Gyeongnam Province, Korea: A retrospective review of 1,292Cases over 19 Years (1995~2013). Annals of Dermatology 28(2): 172-178.

Edlich, R.F., Becker, D.G., Long, W.B. & Masterson, T.M. 2004. Excisional biopsy of skin tumors. Journal of Long-Term Effects of Medical Implants 14(3): 201-214.

Ferrándiz, C., Malvehy, J., Guillén, C., Ferrándiz-Pulido, C. & Fernández-Figueras, M. 2017.Precancerous skin lesions. Actas Dermo-Sifiliográficas 108(1): 31-41.

Freak, J. 2005. Identification of skin cancers 1: Benign and premalignant lesions. British Journal of Community Nursing 10(1): 8-12.

Furue, M., Yamazaki, S., Jimbow, K., Tsuchida, T., Amagai, M., Tanaka, T., Matsunaga, K., Muto, M., Morita, E., Akiyama, M., Soma, Y., Terui, T. & Manabe, M. 2011. Prevalence of dermatological disorders in Japan: a nationwide, cross-sectional, seasonal, multicenter, hospital-based study. The Journal of Dermatology 38(4): 310-320.

Gogi, A.M. & Ramanujam, R. 2013. Clinicopathological study and management of peripheral soft tissue tumours. Journal of Clinical and Diagnostic Research 7(11): 2524-2526.

Higgins, J.C., Maher, M.H. & Douglas, M.S. 2015. Diagnosing common benign skin tumors. American Family Physician 92(7): 601-607.

Hwang, S-M., Pan, H-C., Hwang, M-K., Kim, M-W. & Lee, J-S. 2016. Malignant skin tumor misdiagnosed as a benign skin lesion. Archives of Craniofacial Surgery 17(2): 86-89.

Ingraffea, A. 2013. Benign skin lesions. Facial Plastic Surgery Clinics of North America 21(1): 21-32.

Kanitakis, J. 2010. Adnexal tumours of the skin as markers of cancer-prone syndromes. Journal of the European Academy of Dermatology and Venereology 24(4): 379-387.

Kartal, D., Cinar, S.L., Akin, S., Ferahbas, A. & Borlu, M. 2015. Skin findings of geriatric patients in Turkey: A 5-year survey. Dermatol Sinica 33(4): 196-200.

Kasraeian, S., Allison, D.C., Ahlmann, E.R., Fedenko, A.N. & Menendez, L.R. 2010. A Comparison of fine-needle aspiration, core biopsy, and surgical biopsy in the diagnosis of extremity soft tissue masses. Clinical Orthopaedics and Related Research 468(11): 2992-3002.

Kim, H.S., Cho, E.A., Bae, J.M., Yu, D.S., Oh, S.T., Kang, H., Park, C.J., Lee, J.D., Lee, J.Y.,Kim, S.Y., Kim, H.O. & Park, Y.M. 2010. Recent trend in the incidence of premalignant and malignant skin lesions in Korea between 1991 and 2006. Journal of Korean Medical Science 25(6): 924-929.

Kyriakis, K.P., Alexoudi, I., Askoxylaki, K., Vrani, F. & Kosma, E. 2012. Epidemiologic aspects of seborrheic keratoses. International Journal of Dermatology 51(2): 233-234.

Layfield, L.J., Schmidt, R.L., Sangle, N. & Crim, J.R. 2014. Diagnostic accuracy and clinical utility of biopsy in musculoskeletal lesions: A comparison of fine-needle aspiration, core, and open biopsy techniques. Diagnostic Cytopathology 42(6): 476-486.

LeBoit, P.E. (Philip E); International Agency for Research on Cancer; World Health Organization; International Academy of Pathology; European Organization for Research on Treatment of Cancer; UniversitätsSpital Zürich Departement Pathologie. 2006. Pathology and Genetics of Skin Tumours. Lyon: IARC Press pp. 9-291.

Lee, E.H., Nehal, K.S. & Disa, J.J. 2010. Benign and premalignant skin lesions. Plastic and Reconstructive Surgery 125(5): 188e-198e.

Luba, M.C., Bangs, S.A., Mohler, A.M. & Stulberg, D.L. 2003. Common benign skin tumors. American Family Physician 67(4): 729-738.

Mohammedamin, R.S., van der Wouden, J.C., Koning, S., van der Linden, M.W., Schellevis, F.G., van Suijlekom-Smit, L.W. & Koes, B.W. 2006. Increasing incidence of skin disorders in children? A comparison between 1987 and 2001. BMC Dermatology 6: 4.

Murray, C.J., Lopez, A.D., Black, R., Mathers, C.D., Shibuya, K., Ezzati, M., Salomon, J.A., Michaud, C.M., Walker, N. & Vos, T. 2007. Global burden of disease 2005: Call for collaborators. Lancet 370(9582): 109-110.

Nguyen, T. & Zuniga, R. 2013. Skin conditions: Benign nodular skin lesions. FP Essentials 407: 24-30.

Pujani, M., Madaan, G., Jairajpuri, Z., Jetley, S., Hassan, M. & Khan, S. 2016. Adnexal tumors of skin: An experience at a tertiary care center at Delhi. Annals of Medical and Health Sciences Research 6(5): 280-285.

Sinikumpu, S-P., Huilaja, L., Jokelainen, J., Koiranen, M., Auvinen, J., Hägg, P.M., Wikström, E., Timonen, M. & Tasanen, K. 2014. High prevalence of skin diseases and need for treatment in a middle aged population. A Northern Finland Birth Cohort 1966 Study. PLoS ONE 9(6): e99533.

Wakely, P.E. Jr. & Kneisl, J.S. 2000. Soft tissue aspiration cytopathology. Cancer 90(5): 292-298.

Woon, D.T.S & Serpell, J.W. 2008. Preoperative core biopsy of soft-tissue tumours facilitates their surgical management: A 10 year update. ANZ Journal of Surgery 78(11): 977-981.

 

*Pengarang untuk surat-menyurat; email: dr.s.destek@gmail.com

 

 

 

 

 

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