Sains Malaysiana 49(6)(2020): 1273-1282

http://dx.doi.org/10.17576/jsm-2020-4906-05

 

Ameliorative Effect of Apple Pomace and Mango Peels against Hyperlipidemia and Lipid Peroxidation Induced by Hyperlipidemic Diet

 (Kesan Amelioratif Buah Epal dan Kulit Mangga terhadap Hiperlipidemia dan Peroksidasi Lipid disebabkan oleh Diet Hiperlipidemik)

 

HUMA UMBREEN1*, MUHAMMAD UMAIR ARSHAD1, RAZIA NOREEN2 & KIRAN AFTAB3

 

1Institute of Home and Food Sciences, GC University, Faisalabad, Pakistan

 

2Department of Biochemistry, GC University, Faisalabad, Pakistan

 

3Department of Chemistry, GC University, Faisalabad, Pakistan

 

Diserahkan: 18 Oktober 2018/ Diterima: 17 Februari 2020

 

ABSTRACT

Diet induced hyperlipidemia is a major cause for atherosclerosis, lipid peroxidation, and fatty liver diseases. Fruit processing waste rich in dietary fiber and antioxidant capacity can be an economical way to manage such risk factors. The major objective of the present study was to manage hyperlipidemia by including apple pomace and mango peels in daily diet. Dry powder obtained from apple pomace, mango peels and their mixture was added to the normal chow on replacement basis by 12%. These were fed to the rats along with hyperlipidemic diet to the experimental groups (N=30, 10/group), while control group (N=10) was fed hyperlipidemic diet alone. The rats were analyzed for water and feed intake, body weight, organs to body weight ratio, glucose concentration, lipid profile, lipid peroxidation test, liver cholesterol, and liver and renal function tests. The results showed that high cholesterol in diet was well managed by rat groups on apple pomace and mango peels supplement. The mango peels powder was found to be more effective as compared to apple pomace powder against hyperlipidemia. Mango peels and apple pomace powders not only improved the lipid profile but also resulted in lower liver cholesterol concentration and better lipid peroxidation status of the experimental rats as compared to control group. It can be concluded that fruit processing waste specially mango peels can be cost effective tool to manage diet induced hyperlipidemia, lipid peroxidation and fatty liver diseases.

 

Keywords: Antioxidants; fiber; fruit waste; lipid peroxidation; liver cholesterol

 

ABSTRAK

Diet teraruh hiperlipidemia adalah penyebab utama aterosklerosis, peroksidasi lipid dan penyakit hati berlemak. Serat pemakanan yang kaya dengan sisa pemprosesan buah dan keupayaan antioksidan boleh dijadikan sebagai satu cara yang ekonomi untuk menguruskan faktor risiko tersebut. Objektif utama kajian ini adalah untuk menguruskan hiperlipidemia dengan memasukkan buah epal dan kulit manga dalam diet harian. Serbuk kering yang diperoleh daripada buah epal, kulit manga dan campuran tersebut telah ditambahkan ke dalam chow biasa secara penggantian sebanyak 12%. Makanan diberikan kepada tikus dengan diet hiperlipidemik bagi kumpulan uji kaji (N=30, 10/kumpulan), manakala kumpulan kawalan (N=10) diberi makanan diet hiperlipedemik sahaja. Tikus dianalisis untuk pengambilan air dan makanan, berat badan, nisbah berat organ kepada badan, kepekatan glukosa, profil lipid, ujian peroksidasi lipid, kolesterol hati dan ujian fungsi hati dan ginjal. Hasil kajian menunjukkan bahawa kolesterol tinggi dalam makanan dapat dikendalikan dengan baik oleh kumpulan tikus dengan bahan tambahan buah epal dan kulit mangga. Serbuk kulit mangga didapati lebih berkesan jika dibandingkan dengan serbuk buah epal terhadap hiperlipidemia. Serbuk kulit mangga dan buah epal bukan sahaja meningkatkan profil lipid tetapi juga menghasilkan kepekatan kolesterol hati yang lebih rendah dan status peroksidasi lipid yang lebih baik bagi tikus eksperimen berbanding dengan kumpulan kawalan. Ini dapat disimpulkan bahawa sisa pemprosesan buah khususnya kulit mangga dapat menjadi alat yang efektif daripada segi kos untuk menguruskan hiperlipidemia yang disebabkan oleh diet, peroksidasi lipid dan penyakit hati berlemak.  

 

Kata kunci: Antioksida; kolesterol hati; peroksidasi lipid; serat; sisa buah

 

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*Pengarang untuk surat-menyurat; email: huma_umbreen@yahoo.com

 

 

 

 

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