The Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia is pleased to introduce a new research facility featuring the Agilent Seahorse XF HS Mini, an advanced instrument designed to analyse mitochondrial function and cellular metabolism in real time with high sensitivity.

This system enables researchers to perform detailed bioenergetic analysis by simultaneously measuring the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in live cells. Such capability provides valuable insights into cellular metabolic processes across various research areas including cancer metabolism, immune cell metabolism, and general cellular physiology.

Key advantages of the instrument include high sensitivity for small sample volumes, label-free real-time detection in live cells, and integrated data analysis software that facilitates efficient data processing and interpretation.

The analyser supports a wide range of metabolic assays including the Real-Time ATP Rate Assay, Cell Mito Stress Test, Mito Tox Assay, T Cell Metabolic Profiling, and Glycolytic Rate Assay. These assays allow researchers to investigate cellular energy production, mitochondrial respiration, mitochondrial toxicity, and glycolytic activity in a comprehensive manner.

This facility is expected to strengthen the research capabilities of the Department of Biochemistry and support various biomedical research projects. Researchers, postgraduate students, and collaborators who are interested in utilising this facility are welcome to contact the department for further information regarding access and research collaboration.