UKM Medical Molecular Biology Institute

 Leading Institute in Molecular Medicine

PRIME Researchers

Principal Investigators

Professor Chim Lang
(Principal Investigator, UoD)


Professor Lang is a translational cardiologist with a track record in research excellence in the area of cardiovascular complications of T2D. He has published more than 250 papers in major journals, including NEJM, Lancet, European Heart Journal, JACC, and Circulation. He has an H factor of 57. He is WP Co-Lead in the IMI2-CARDIATEAM project on diabetic cardiomyopathy and a WP lead in the FP-7 BIOSTAT system biology project on heart failure and is the Chief Investigator of the BHF funded MET-REMODEL and RECEDE trials and the EFSD funded REFORM trial.


Professor Rahman Jamal
(Principal Investigator, Malaysia) 


Professor Rahman Jamal is a senior principal research fellow and the founding director of the UKM Medical Molecular Biology Institute (UMBI). He is a Professor of Paediatric Haematology & Oncology and Molecular Biology at the Faculty of Medicine UKM. He obtained his Ph.D. from University College London. He is currently the Principal Investigator for The Malaysian Cohort project which follows closely the aims and protocols of the UK Biobank. He also leads a number of research teams focusing on cancers and also non-communicable diseases including diabetes. He is a fellow of the Academy Sciences Malaysia as well as the chairman of the National Subcommittee for Ethics in Cell Therapy and Research. He has published more than 160 indexed journal articles that cover the areas of cancer genomics and non-communicable diseases.

 UKM Sarjana 


Co-Investigators University of Dundee (UoD)

Professor Colin Palmer

Professor Colin Palmer has a major international reputation in relation to his research on the identification of the genetic basis of phenotypic traits and complex diseases and pharmacogenetics. He has an H factor of 71; his papers have been cited over 24,000 times. He pioneered population pharmacogenetic research, with the establishment of the GoDARTS/GoSHARE cohorts, now a major resource for the study of diabetes with >40,000 patients and controls with linkage to complete electronic medical records. The development of these unique resources allowed him to play a key role in the discovery of genes for T2D, cardiovascular disease, and obesity, including trans-ethnic collaborations with Dr. Mohan and many other Asian groups. This has led to the establishment of the NIHR-funded INSPIRED collaboration in India, providing key experience directly related to PRIME.


Professor Emanuele Trucco


Professor Emanuele Trucco is the director of the VAMPIRE programme, created more than 10 years ago with the University of Edinburgh (Dr. T MacGillivray), and co-leads the Computer Vision and Image Processing (CVIP) group which carries out research on medical image and video processing, machine/deep learning, and data analysis. VAMPIRE software is in use in clinical research in Europe, Asia, and the Americas.

Professor Ewan Pearson


Professor Ewan Pearson is Professor in Diabetic Medicine. His research interests are the phenotypic and genotypic determinants of drug response, the aetiology of young-onset diabetes, and the mechanisms driving the progression of diabetes. He leads the IMI-DIRECT project on stratification in Type 2 diabetes and is a co-lead on the  MRC funded MASTERMIND project and holds a Wellcome Trust New Investigator award to investigate drug response in Type 2 diabetes.

Dr. Alexander Doney


Dr. Alexander Doney is Senior Lecturer and Honorary NHS Consultant who pioneered and established the original proof of principle of linking genomic data with electronic records at the University of Dundee and played a significant role in the development and clinical application of the VAMPIRE retinal imaging platform.

Dr. Ify Mordi 


Dr. Ify Mordi specialises in clinical research linking electronic health records and genomic data to elucidate novel biomarkers and mechanisms underlying the relationship between T2D and cardiovascular outcomes.


Co-Investigators (Malaysia)

Associate Professor Dr. Norlaila Mustafa


Associate Professor Dr. Norlaila Mustafa is a senior endocrinologist at the Faculty of Medicine, Universiti Kebangsaan Malaysia, and has participated in many research projects related to diabetes including genetic studies. She has an MD from Cardiff University, UK.

UKM Sarjana

Datuk Dr. Aizai Azan Abdul Rahim


Datuk Dr. Aizai Azan Abdul Rahim is a senior cardiologist at the National Heart Institute in Kuala Lumpur.


Associate Professor Dr. Nor Azian Murad


Associate Professor Dr. Nor Azian Murad is the present director at the UKM Medical Molecular Biology Institute, UKM. She has numerous papers related to diabetes, mostly related to GWAS and whole-exome sequencing. She obtained her Ph.D. degree from the Queensland Institute of Medical Research, Australia.

UKM Sarjana


Associate Professor Dr. Jemaima Che Hamzah


Associate Professor Dr. Jemaima Che Hamzah is a senior ophthalmologist at the Faculty of Medicine, Universiti Kebangsaan Malaysia. She has published in the field of ophthalmology including publications on retinal diseases. She obtained her Ph.D. degree from the University of Aberdeen, UK.

UKM Sarjana

Dr. Siti Aishah Sulaiman

Dr. Siti Aishah Sulaiman is a research fellow at UMBI and her research focus is on the genomics of diabetes.

UKM Sarjana

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