Sains Malaysiana 50(8)(2021): 2379-2393

http://doi.org/10.17576/jsm-2021-5008-20

Evaluating the Potential of Pyriproxyfen Dissemination using Mosquito Home System against Aedes albopictus at a Dengue Hotspot Area

(Menilai Potensi Penyebaran Pyriproxyfen menggunakan Sistem Rumah Nyamuk terhadap Aedes albopictus di Satu Kawasan 'Titik Panas' Denggi)

AHMAD MOHIDDIN MOHD NGESOM¹, NAZNI WASI AHMAD²,  LEE HAN LIM², ASMALIA MD LASIM³, DAVID GREENHALGH⁴, MAZRURA SAHANI¹, ROZITA HOD⁵ & HIDAYATULFATHI OTHMAN¹*

¹Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Federal Territory, Malaysia

²Medical Entomology Unit, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Federal Territory, Malaysia

³Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor Darul Ehsan, Malaysia

⁴Department of Mathematics and Statistics, University of Strathclyde, 16, Richmond Street, Glasgow, G11XQ, United Kingdom

⁵Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Federal Territory, Malaysia

Received: 30 March 2020/Accepted: 31 December 2020

ABSTRACT

Aedes mosquitoes were found to lay their eggs in the cryptic breeding sites. Eliminating cryptic and open breeding sites is essential in reducing dengue virus transmission. However, it is often challenging for health officers to assess these breeding sites which are usually missed during larval surveillance. The autodissemination approach may produce a better outcome by manipulating female mosquitoes to disperse insecticide to other Aedes spp. mosquito habitats. Thus, the present study aims to evaluate the effectiveness of the pyriproxyfen autodissemination technique using Mosquito Home System against the population of mosquitoes. This study was conducted in Bandar Baru Bangi, Selangor, Malaysia. The Mosquito Home System was deployed to control Aedes spp. populations at treatment sites using before-after-control-impact (BACI) design. The presence of pyriproxyfen distribution was confirmed using  the WHO larval bioassay which resulted in 10-35% larvae mortalities. Autodissemination of pyriproxyfen significantly reduced the population size of mosquito eggs (p<0.05), larvae (p<0.05), and ovitrap index (p<0.05) at the treatment areas compared to the control areas. Moreover, rainfall was correlated positively against ovitrap index (r = 0.247), larvae (r = 0.420), and eggs (r = 0.422). The study provides promising results for controlling Aedes spp. populations and also highlights the potentials of this technique as an alternative in vector control programmes. However, further studies on larger scale field trials are warranted.

Keywords: Aedes; autodissemination; emergence inhibition; pyriproxyfen; vector control

ABSTRAK

Nyamuk Aedes ditemui bertelur di kawasan pembiakan yang tersembunyi. Penghapusan bekas tersembunyi dan terbuka adalah penting bagi mengurangkan penularan virus denggi. Walau bagaimanapun, kawasan pembiakan ini sukar dikesan oleh anggota kesihatan dan lazimnya diabaikan semasa pemantauan larva. Kaedah penyebaran-auto memberikan keputusan yang baik dengan memanipulasi nyamuk betina untuk memindahkan insektisid ke habitat nyamuk Aedes. Oleh itu, kajian ini adalah untuk menilai keberkesanan kaedah penyebaran-auto pyriproxyfen menggunakan Sistem Rumah Nyamuk terhadap populasi nyamuk liar. Kajian ini dijalankan di Bandar Baru Bangi, Selangor. Sistem Rumah Nyamuk digunakan untuk mengawal populasi Aedes spp. di lokasi rawatan dengan kaedah sebelum-selepas-kawalan-impak. Kehadiran penyebaran pyriproxyfen dibuktikan dengan bioasai larva WHO telah menunjukkan 10-35% mortaliti larva. Penyebaran pyriproxyfen secara signifikan menurunkan saiz populasi telur nyamuk (p<0.05), larva (p<0.05) dan indeks ovitrap (p<0.05) di kawasan rawatan berbanding kawasan kawalan. Selain itu, taburan hujan berkorelasi secara positif terhadap indeks ovitrap (r = 0.247), larva (r = 0.420) dan telur (r = 0.422). Kajian ini memberikan keputusan yang memberangsangkan dalam mengawal populasi Aedes spp. dan menyerlahkan potensi kaedah ini sebagai alternatif dalam program kawalan vektor. Walau bagaimanapun, kajian lapangan pada skala besar adalah satu keperluan.

Kata kunci: Aedes; kawalan vektor; penyebaran-auto; perencatan tumbesaran; pyriproxyfen

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*Corresponding author; email: hida@ukm.edu.my