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Faculty of Pharmacy, UKM

Advancing Pharmacy For Health

Associate Prof. Dr. Ng Shiow Fern

Position Chair, Centre for Drug Delivery Technology Research, UKM
Coodinator, Discipline of Pharmaceutics
Qualifications PhD (in Pharmaceutical Sciences), University of Strathclyde Master of Pharmacy (Hons), IMU-University of Strathclyde
Research summary

Dr Shiow-Fern Ng received her Ph.D. in Pharmaceutical Sciences in 2007 from the University of Strathclyde (Glasgow, UK). She is currently an Associate Professor in the Faculty of Pharmacy UKM.

She holds many administrative positions in the Faculty. This includes the Coordinator of e-Learning (2012-2017), Coordinator of Discipline of Pharmaceutics (2018-2021), Chair of the Centre of Drug Delivery Technology Research (2020-2022). She is a registered pharmacist and currently she serves as the President of the MyCRS, Controlled Release Society the Malaysia Local Chapter (2018-2020).

Throughout her academic career, she has obtained publication award in top tier Journals (2016, 2017, 2018), Teaching Innovation Award (2014, 2017), Outstanding industry collaboration award (2017).

Teaching

Programmes: Bachelor of Pharmacy,
Master of Pharmaceutical Analysis UKM

No.

Semester

Course Code

Course Name

1.

1

NFNF3273

Industrial Pharmacy

2.

1

NFNA6013

Advanced Methods in Pharmaceutical Analysis

3.

1

NFNF2213

Pharmaceutical Product Development I

4.

1

NFNA6094

Research Project I

5.

1

NFNA6213

Pharmaceutical Dosage Form Design

6.

1

NFNF1213

Drug Physicochemical Properties

7.

2

NFNF2552

Cosmeceuticals

8.

2

NFNF2283

Pharmaceutical Product Development II

9.

2

NFNF3624

Research Project II

10.

2

NFNF1223

Formulation Sciences

Research

Her current research interests focus on drug delivery, through the exploitation of delivery of therapeutic agents to chronic wounds as well as the application of various biopolymers for the retention and delivery of active compounds, for a variety of potential wound therapeutic applications. As of 2020, she has supervised 6 PhD students and 11 Masters students. Research collaborators include local pharmaceutical industries and institutions as well as institutions in South East Asia – Singapore, Thailand, Philippines, and Vietnam. Dr Ng also works very closely with wound care unit in Kuala Lumpur General Hospital to translate her research output into potential clinical applications

Areas of Research Interests

  • Preformulation studies
  • Physical and chemical characterizations of drug delivery systems
  • In vitro and in vivo testings of topical and transdermal formulations
  • Films and Freeze-dried polymeric systems for drug delivery
  • Formulation of mucosal (wounds) drug delivery systems.
  • The interaction of skin tissues and polymeric biomaterials.
  • Nano formulations and liposomal dispersions
  • Infection associated with wound biomaterials and strategies for its prevention.
  • Wound dressings/wound delivery systems

Publications

Journals (2015-2020)

  • Loh, Evelyn Yun Xi, Mh Busra Fauzi, Min Hwei Ng, Pei Yuen Ng, Shiow Fern Ng, and Mohd Cairul Iqbal Mohd Amin (2020). Insight into Delivery of Dermal Fibroblast by Non-Biodegradable Bacterial Nanocellulose Composite Hydrogel on Wound Healing. International Journal of Biological Macromolecules 159: 497-509. (Q1, ISI/Scopus)
  • Tan Woan Sean, Palanisamy Arulselvan, Shiow-Fern Ng, Che Norma Mat Taib, Murni Nazira Sarian, Sharida Fakurazi (2020). Development Vicenin-2 Hydrocolloid Film Based Alginate Due to Its In Vitro Healing Effect on Human Dermal Fibroblast. BioMed Research International, 2020. 2020: p. 4730858. (Q2, ISI/Scopus)
  • Chai-Yee Chin, Shiow-Fern Ng (2020). Moringa Oleifera Standardised Leaf Extract Electrospun Nanofibers Impregnated onto Alginate-Pectin Hydrocolloid Film as A Potential Delayed Chronic Wound Dressing. Fibers and Polymers (Accepted Q2, ISI/Scopus)
  • Nur Izzah Md Fadilah, Haslina Ahma, Mohd Basyaruddin Abdul Rahman Chia Suet Lin, Shiow- Fern Ng. (2020). Synthesis, Characterization and In Vitro Evaluation of a Small Palmitoyl-Tetrapeptide Potential for Wound Healing. Journal of Saudi Chemical Society, 24(8): p. 606-619. (Q2, ISI/Scopus)
  • Ai-Wei Lim, Pei-Yuen Ng, Norman Chieng, Shiow-Fern Ng. (2019) Moringa oleifera Leaf Extract–Loaded Phytophospholipid Complex for Potential Application as Wound Dressing. Journal of Drug Delivery Science and Technology. 54, 101329. (Q2, ISI/Scopus)
  • Taradokht Alavi, Masoud Rezvanian, Naveed Ahmad, Najwa Mohamad, Shiow-Fern Ng. (2019) Pluronic-F127 composite film loaded with erythromycin for wound application: formulation, physicomechanical and in vitro evaluations. Drug Delivery and Translational Research. 9(2):508-519. (Q2, ISI/Scopus)
  • Muhammad Irfan Siddique, Haliza Katas, Adawiyah Jamil, Mohd Cairul Iqbal Mohd Amin, Shiow-Fern Ng, Mohd Hanif Zulfakar, Syed Maaz Nadeem. (2019) Potential treatment of atopic dermatitis: tolerability and safety of cream containing nanoparticles loaded with hydrocortisone and hydroxytyrosol in human subjects. Drug Delivery and Translational Research. 9(2): 469–481. (Q2, ISI/Scopus)
  • Woan Sean Tan, Palanisamy Arulselvan, Shiow-Fern Ng, Che Norma Mat Taib, Murni Nazira Sarian and Sharida Fakurazi. (2019) Improvement of diabetic wound healing by topical application of Vicenin-2 hydrocolloid film on Sprague Dawley rats. BMC Complementary and Alternative Medicine. 19:20. (Q2, ISI/Scopus)
  • Anam Anjum, Chung Pooi-Yin, Shiow-Fern Ng. (2019) PLGA/xylitol nanoparticles enhance antibiofilm activity via penetration into biofilm extracellular polymeric substances. RSC Advances 9, 14198-14208. (Q2, ISI/Scopus)
  • Nor Hazwan Ali, Mohd Cairul Iqbal Mohd Amin, Shiow-Fern Ng. (2019) Sodium Carboxymethyl Cellulose Hydrogels Containing Reduced Graphene Oxide (rGO) as a Functional Antibiofilm Wound Dressing. Journal of Biomaterials Science, Polymer Edition. 30 (8): 629-645 (Q2, ISI/Scopus)
  • Chai-Yee Chin, Pei-Yuen Ng, Shiow-Fern Ng (2019). Moringa oleifera standardised aqueous leaf extract-loaded hydrocolloid film dressing: in vivo dermal safety and wound healing evaluation in STZ/HFD diabetic rat model. Drug Delivery and Translational Research. 9, 453–468 (Q2, ISI/Scopus)
  • Xi Loh, Evelyn Yun, Mh Busra Fauzi, Min Hwei Ng, Pei Yuen Ng, Shiow Fern Ng, Hidayah Ariffin, and Mohd Cairul Iqbal Mohd Amin. (2018). Cellular and Molecular Interaction of Human Dermal Fibroblasts with Bacterial Nanocellulose Composite Hydrogel for Tissue Regeneration. ACS Applied Materials & Interfaces 10, no. 46: 39532-43. (Q1, ISI/Scopus)
  • Evelyn Loh Yun Xi, Najwa Mohamad, Mh Busra Fauzi, Ng Min Hwei, Shiow Fern Ng, Amin, Mohd Cairul Iqbal Mohd. (2018) Development of a bacterial cellulose-based hydrogel cell carrier containing keratinocytes and fibroblasts for full-thickness wound healing. Scientific Reports 8:2875. (Q1, ISI/Scopus)
  • Anam Anjum, Cai-Hong Sim, Shiow-Fern Ng (2018). Hydrogel containing antibiofilm agents and antimicrobial beneficial for biofilm-associated wound infection: formulation, characterisation and in vitro study. AAPS PharmSci Tech 19(3):1219-1230 (Q2, ISI/Scopus)
  • Chai-Yee Chin, Juriyati Jalil, Pei-Yuen Ng, Shiow-Fern Ng (2018). Development and Formulation of Moringa oleifera standardised leaf extract film dressing for wound healing application. Journal of Ethnopharmacology. 212:188-199. (Q1, ISI/Scopus)
  • Rezvanian M, Ahmad N, Mohd Amin MC, Shiow-Fern Ng. (2017). Optimization, characterization, and in vitro assessment of alginate-pectin ionic cross-linked hydrogel film for wound dressing applications. Int J Biol Macromol. 97:131-140. (Q1, ISI/Scopus)
  • Hussain Z, Thu HE, Shiow-Fern Ng, Khan S, Katas H. (2017). Nanoencapsulation, an efficient and promising approach to maximize wound healing efficacy of curcumin: A review of new trends and state-of-the-art. Colloids Surf B Biointerfaces. 150:223-24. (Q1, ISI/Scopus)
  • Leong-Seng Tan, Fhataheya Buang, Shiow-Fern Ng. (2017). Transdermal anti-inflammatory activity of bilayer film containing olive compound hydroxytyrosol: physical assessment, in vivo dermal safety and efficacy study in Freund’s adjuvant-induced arthritic rat model. Drug Development Industrial Pharmacy 43(1):108-119. (Q3, ISI/Scopus).
  • Masoud Rezvanian, Chin-Khai Tan, Shiow- Fern Ng. (2016). Simvastatin-loaded lyophilized wafers as a potential dressing for chronic wounds. Drug Development Industrial Pharmacy. Jun 24:1-8  (Q2, ISI/Scopus)
  • Jordan Chia-Yung Lai, How-Yee Lai, Nalamolu Koteswara Rao, Shiow-Fern Ng. (2016). Treatment for diabetic ulcer wounds using a fern tannin optimized hydrogel formulation with antibacterial and antioxidative properties. Journal of Ethnopharmacology 189:277-89. (Q1, ISI/Scopus)
  • Muhammad Irfan Siddique1, Haliza Katas, Mohd Cairul Iqbal Mohd Amin, Shiow-Fern Ng, Mohd Hanif Zulfakar, Fhataheya Buang, Adawiyah Jamil. (2016). In-Vivo Dermal Pharmacokinetics, Efficacy, and Safety of Skin Targeting Nanoparticles for Corticosteroid Treatment of Atopic Dermatitis. International Journal of Pharmaceutics. 507(1-2). 72-82. (Q1, ISI/Scopus)
  • Masoud Rezvanian, Mohd Cairul Iqbal Mohd Amin, Shiow-Fern Ng (2016). Development and Physicochemical Characterisation of Alginate Composite Biopolymer Hydrocolloid Film Loaded with Simvastatin as a Wound Dressing. Carbohydrate Polymers. 137:295-304 (Q1, ISI/Scopus)
  • Shiow-Fern Ng, Say-Lee Tan (2015). Alginate Bilayer Films Containing Olive compound Hydroxytyrosol as an Alternative for Topical Chemotherapy. International Journal of Pharmaceutics 495 (2); 798-806. (Q1, ISI/Scopus)
  • Muhammad Irfan Siddique1, Haliza Katas, Mohd Cairul Iqbal Mohd Amin, Shiow-Fern Ng, Mohd Hanif Zulfakar, Fhataheya Buang, Adawiyah Jamil. (2015). Minimization of local and systemic adverse effects of topical glucocorticoids by nanoencapsulation; In-vivo safety of hydrocortisone-hydroxytyrosol loaded chitosan nanoparticles. Journal of Pharmaceutical Sciences 104(12): 4276-4286 (Q2, ISI/Scopus).
  • Khairul Anuar Khairoji, Manira Maarof , Min Hwei Ng, Shiow-Fern Ng, Aminuddin Bin Saimd, Ruszymah Hj Idrusa (2015). Tissue Engineered Bilayered Skin For Drug Diffusion Studies. Regenerative Research 4(1), 37- 44.
  • Shiow-Fern Ng, Nurul-Asmaa Anuwi, Tengku-Noraisyah Tengku-Ahmad. (2015) Topical Lyogel Containing Corticosteroid Decreases IgE Expression and Enhances the Therapeutic Efficacy of Atopic Eczema in Mice Model. AAPS PharmSciTech 16(3):656-63. (Q3, ISI/Scopus)
  • Shiow-Fern Ng, Hon-Lunn Leow (2015). Development of biofilm-targeted antimicrobial wound dressing for the treatment of chronic wound infections. Drug Dev Ind Pharm 25:1-8 (Q3, ISI/Scopus).

Book Chapters

  • Shiow-Fern Ng. (2020) Luka Terbakar. Dlm: Ensiklopedia Nanoteknologi. Dewan Bahasa and Pustaka (Malaysia).
  • Shiow-Fern Ng. (2020) Chapter 7: Freeze Dried Wafers for Wound Healing. In: Therapeutic Dressings and Wound Healing Applications. Joshua Boateng (Ed) Wiley Publishing (UK). Page 137 – 156.
  • Shiow-Fern Ng. (2019) Penyembuhan Luka Dan Perkembangan Semasa Sistem Penghantaran Dadah Bagi Merawat Luka. Dlm: Teknologi Penghantaran Dadah dalam Perubatan 57-67. UKM Press (Malaysia).

Awards And Recognitions

  • Excellent Service Award 2011,2018, Universiti Kebangsaan Malaysia
  • Publication Award in Journal Q1 and Q2 2019, Universiti Kebangsaan Malaysia
  • Excellent Teaching Award 2018 (Hari Kualiti Fakulti Farmasi), Universiti Kebangsaan Malaysia
  • Excellent Publication Award (in General Writing) 2018 (Hari Kualiti Fakulti Farmasi), Universiti Kebangsaan Malaysia
  • Excellent Research Award 2018 (Hari Kualiti Fakulti Farmasi), Universiti Kebangsaan Malaysia
  • Publication Award in Journal Q1 and Q2 2018, Universiti Kebangsaan Malaysia
  • Publication Awards (Catergory: Scientific Journals) 2016 & 2017, Universiti Kebangsaan Malaysia
  • Industry Engagement Awards (Category: Innovative Research Category) 2016, Universiti Kebangsaan Malaysia
  • Excellent Teaching Innovation Award 2014 , Universiti Kebangsaan Malaysia
  • Most Active e-Learning Award (University Category) Semester 1&2, 2013-2014, University Kebangsaan Malaysia
  • Most Active Course Award (Pharmaceutical Technology) 2011-2012, Universiti Kebangsaan Malaysia
  • The Best Oral Presentation for Pharmaceutics Category, The 7th IndoPharma Pharmaceutical Sciences Conference, Bangkok, Thailand, 2011.
  • The Best Poster Award, Research Day, Fakulti Farmasi UKM. 2011
  • Best Lead Scholar Group (3rd Place) 2008, Universiti Kebangsaan Malaysia
  • D. Scholarship and Studentship awarded by GlaxoSmithKline(UK) and University of Strathclyde (Glasgow) 2003
  • MPharm Scholarship awarded by National Higher Education Fund (PTPTN) 2002 – Loan conversion to full scholarship due to achievement of 1st Class Honours.