3.4.2026 – UMBI Research Updates Series (RUS) in Molecular Medicine
3 April 2026 | The ๐๐๐ฌ๐๐๐ซ๐๐ก ๐๐ฉ๐๐๐ญ๐ ๐๐๐ซ๐ข๐๐ฌ ๐ข๐ง ๐๐จ๐ฅ๐๐๐ฎ๐ฅ๐๐ซ ๐๐๐๐ข๐๐ข๐ง๐ ๐๐จ.๐/๐๐๐๐ was successfully held earlier this morning, featuring engaging and thought-provoking presentations by two of UMBIโs Research Fellows.
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๐๐ฌ๐ฌ๐จ๐๐ข๐๐ญ๐ ๐๐ซ๐จ๐๐๐ฌ๐ฌ๐จ๐ซ ๐๐ซ. ๐๐๐จ๐ก ๐๐ฎ๐ข-๐ฆ๐ข๐ง presented #๐๐๐: ๐๐๐ข๐๐ง๐๐ ๐ข๐ฌ ๐๐จ๐ญ ๐ญ๐ก๐ ๐๐๐ฉ, highlighting the importance of molecular typing and surveillance in tackling antimicrobial resistance (AMR). Initiated as early as 2009 and revisited in 2017, the effort reflects a strong collaboration between UMBI, the Infection Control Unit, and the Department of Microbiology & Immunology. Moving beyond conventional bacterial identification and antibiotic susceptibility testing, her work focuses on identifying circulating genotypes within hospital settings. She also shared regional insights comparing MRSA trends across Malaysia, Singapore, and Thailand, and introduced the Swiss cheese model as a framework to understand gaps in AMR control.
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๐๐ซ. ๐๐๐ ๐๐๐ฒ ๐๐๐ delivered an insightful session titled ๐๐ซ๐๐๐ค๐ข๐ง๐ ๐ญ๐ก๐ ๐๐ซ๐จ๐ญ๐๐ข๐ง ๐๐จ๐๐: ๐
๐ซ๐จ๐ฆ ๐๐๐ช๐ฎ๐๐ง๐๐ ๐ญ๐จ ๐๐ญ๐ซ๐ฎ๐๐ญ๐ฎ๐ซ๐ ๐ญ๐จ ๐
๐ฎ๐ง๐๐ญ๐ข๐จ๐ง, exploring how protein binding influences biological activity. Key concepts discussed included protein aggregation and fibrillation, misfolding and degradation, mistransport, and destabilisation. She also introduced AlphaFold2, an advancement that bridges 1D amino acid sequences with 3D structural predictions by directly generating atomic-level coordinatesโrevolutionising protein structure analysis.
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The session fostered meaningful discussions and knowledge exchange, reinforcing UMBIโs commitment to advancing research excellence in molecular medicine. Thank you to all participants for your active engagement and continued support!
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SDG 4 – Quality Education