UKM Medical Molecular Biology Institute

 Leading Institute in Molecular Medicine

– Publication 2014

  1. Jamal R, Syed Zakaria SZ, Kamaruddin MA, Abd Jalal N, Ismail N, Mohd Kamil N, Abdullah A, Baharudin N, Hussin NH, Othman H, Mahadi NM and the Malaysian Cohort Study Group. Cohort profile: The Malaysian Cohort (TMC) project: a prospective study of non-communicable diseases in a multi-ethnic population.
    (2014) Int. J. Epidemiol. Advance Access published pp :1–9. (doi: 10.1093/ije/dyu089.
  2. Hassan, N.Z.A., Mokhtar, N.M., Sin, T.K., Rose, I.M., Sagap, I., Harun, R., Jamal, R. Integrated analysis of copy number variation and genome-wide expression profiling in colorectal cancer tissues (2014) PLoS ONE, 9 (4), art. no. e92553.
  3. Sue Mian Then, Nurul-Faizah Jusoh, Roslan Harun, Sheila Nathan, Nathaniel J. Szewczyk, Louis Stodieck, Rahman Jamal. Multi-generational culture of C. elegans on a long-term space flight revealed changes in expression of genes involved in longevity, DNA repair, and locomotion. (2014) Asia Pac. J. Mol. Med. 4(2):1.
  4. Shah SA, Neoh HM, Rahim SS, Azhar ZI, Hassan MR, Safian N, Jamal R. Spatial analysis of colorectal cancer cases in kuala lumpur. (2014) Asian Pac J Cancer Prev.15(3):1149-54.
  5. Chook, S.W., Chia, C.H., Zakaria, S., Ayob, M.K., Huang, N.M., Neoh, H.M., He, M., Zhang, L., Jamal, R. A graphene oxide facilitated a highly porous and effective antibacterial regenerated cellulose membrane containing stabilized silver nanoparticles (2014) Cellulose. Article in Press.
  6. Nor Azlin Mohamed Ismail, Wan Elly Rushima Wan Abd Rahim, Sharifah Azura Salleh, Hui-min Neoh, Rahman Jamal and Muhammad Abdul Jamil Muhammad Yassin. Seropositivity of Dengue Antibodies During Pregnancy. (2014) The Scientific World Journal. Accepted for publication.
  7. Junaida Osman, Nor Azian Abdul Murad, Siok-Fong Chin, Rahman Jamal. Highly sensitive and reliable human sex determination using multiplex pcr. (2014) Asia Pac. J. Mol. Med. 4(1):1.
  8. Lokamani I, Looi ML, Md Ali SA, Mohd Dali AZ, Ahmad Annuar MA, Jamal R. Gelsolin and ceruloplasmin as potential predictive biomarkers for cervical cancer by 2D-DIGE proteomics analysis. (2014) Pathol Oncol Res, 20(1):119-29.
  9. Hamidah A, Sham Marina M, Tamil AM, Loh CK, Zarina LA, Jamal R, Tuti Iryani MD, Ratnam VC. Parental reports of behavioural outcome among paediatric leukaemia survivors in Malaysia: a single institution experience. (2014) Trop Med Int Health, in press doi: 10.1111/tmi.12358
  10. Chin, K.-Y., Ima-Nirwana, S., Mohamed, I.N., Ahmad, F., Mohd Ramli, E.S., Aminuddin, A., Wan Ngah, W.Z. Serum osteocalcin is significantly related to indices of obesity and lipid profile in Malaysian men (2014) International Journal of Medical Sciences, 11 (2), pp. 151-157.
  11. Chin, K.-Y., Ima-Nirwana, S., Mohamed, I.N., Aminuddin, A., Johari, M.H., Ngah, W.Z.W. The relationships between thyroid hormones and thyroid-stimulating hormone with lipid profile in euthyroid men (2014) International Journal of Medical Sciences, 11 (4), pp. 349-355.
  12. Wan WHN, Kwak MK , Makpol S, Ngah Wan WZ, Yusof Mohd YA. Piper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells (2014) BMC Complementary and Alternative Medicine, 14:72.
  13. Makpol, S., Jam, F.A., Rahim, N.A., Khor, S.C., Ismail, Z., Yusof, Y.A.M., Wan Ngah, W.Z. Comparable down-regulation of TYR, TYRP1 and TYRP2 genes and inhibition of melanogenesis by tyrostat, tocotrienol-rich fraction and tocopherol in human skin melanocytes improves skin pigmentation (2014) Clinica Terapeutica, 165 (1 SUPPL), pp. e39-e45.
  14. Aminuddin, A., Chellappan, K., Maskon, O., Zakaria, Z., Karim, A.A., Ngah, W.Z., Nordin, N.A.M. Augmentation index is a better marker for cardiovascular risk in young Malaysian males: A comparison of involvement of pulse wave velocity, augmentation index, and C-reactive protein (2014) Saudi Medical Journal, 35 (2), pp. 138-146.
  15. Abd Ghafar, N., Chua, K.H., Wan Ngah, W.Z., Che Hamzah, J., Othman, F., Abd Rahman, R., Hj Idrus, R. Phenotypic characterization of culture expanded rabbit limbal corneal keratocytes (2014) Cell and Tissue Banking, 15(1):25-34.
  16. Chin, K.-Y., Ima-Nirwana, S., Mohamed, I.N., Hanapi Johari, M., Ahmad, F., Mohamed Ramli, E.S., Wan Ngah, W.Z. Insulin-like growth factor-1 is a mediator of age-related decline of bone health status in men (2014) Aging Male, 17 (2), pp. 102-106.
  17. Ab Mutalib Nurul-Syakima, Saiful Effendy Syafruddin, Reena Rahayu Md Zain, Ahmad Zailani Hatta Mohd Dali, Rahman Jamal, Ryia Illani Mohd Yunos, Sazuita Saidin and Norfilza M Mokhtar. Molecular Characterization of Serous Ovarian Carcinoma Using a Multigene Next Generation Sequencing Cancer Panel Approach. (2014) BMC Research Notes, 7:805
  18. NurFathiah, A.S., Kenny, D., Suzana, M., Holmen, S.L., Rahman, A.A.J., Wan Zurinah, W.N. Serum GFAP and IGFBP-2 levels on mutated AKT/KRAS induced glioma in the mouse. (2014) Asian Pacific Journal of Tropical Disease, 4 (3), p. 238.
  19. Hasniza Zaman Huri, Mohd Makmor-Bakry, Rosnani Hashim, Norlaila Mustafa, Wan Zurinah Wan Ngah. A Prospective Cohort Study of IRS Genes Polymorphisms in Type 2 Diabetes Mellitus Patients during Severe/Acute Hyperglycemia Phase: Part 1: Association with Insulin Resistance. (2014) Trop J Pharm Res,13(6): 895-901.
  20. Hasniza Zaman Huri, Mohd Makmor-Bakry, Rosnani Hashim, Norlaila Mustafa, Wan Zurinah Wan Ngah. A Prospective Cohort Study of IRS Genes Polymorphisms in Type 2 Diabetes Mellitus Patients during Severe/Acute Hyperglycemia Phase: Part 2: Association with Glycemic Control. (2014) Trop J Pharm Res,13(6):903-906
  21. Hasniza Zaman Huri, Mohd Makmor-Bakry, Rosnani Hashim, Norlaila Mustafa, Wan Zurinah Wan Ngah. Effect of Interaction between Polymorphisms in the Insulin Receptor Substrate Genes in Type 2 Diabetes Mellitus Patients with Severe/Acute Hyperglycemia. (2014) Trop J Pharm Res, 13(6):889-894
  22. Radman, H.M., Yusof, K., Saad, Q.H.M., Ngah, W.Z.W., Abdullah, A. The effect of Ulam raja (Cosmos Caudatus) on Drugmetabolizing Enzymes, Lipid Peroxidation and Antioxidant status in mice liver. (2014) International Journal of PharmTech Research, 6 (4), pp. 1213-1225.
  23. Khor, S.C., Abdul Karim, N., Wan Ngah, W.Z., Mohd Yusof, Y.A., Makpol, S. Vitamin e in sarcopenia: Current evidences on its role in prevention and treatment. (2014) Oxidative Medicine and Cellular Longevity, Article number 914853.
  24. Abdul Rahman, A., A Jamal, A.R., Harun, R., Mohd Mokhtar, N., Wan Ngah, W.Z. Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells. (2014) BMC Complementary and Alternative Medicine, 14:213.
  25. Taridi, N.M., Abd Rani, N., Abd Latiff, A., Wan Ngah, W.Z., Mazlan, M. Tocotrienol Rich Fraction Reverses Age-Related Deficits in Spatial Learning and Memory in Aged Rats. (2014) Lipids. Article in press.
  26. Pek Leng Ng, Nor Fadilah Rajab, Sue Mian Then, Yasmin Anum Mohd Yusof, Wan Zurinah Wan Ngah, Kar Yong Pin, Mee Lee Looi. Piper betle leaf extract enhances the cytotoxicity effect of 5- fluorouracil in inhibiting the growth of HT29 and HCT116 colon cancer cells. (2014) Journal of Zhejiang University SCIENCE B, 15(8): 692-700.
  27. Kok-Yong Chin, Ima-Nirwana Soelaiman, Isa Naina Mohamed & Wan Zurinah Wan Ngah. Pengaruh Umur, Kumpulan Etnik dan Antropometri Badan ke Atas Aras osteokalsin dan Telopeptida Terminal-C Kolagen Jenis I Serum dalam Kalangan Lelaki. (2014) Jurnal Sains Kesihatan Malaysia. 12(1): 7-13.
  28. Amirah Abdul Rahman,Suzana Makpol, Rahman Jamal, Roslan Harun, Norfilza Mokhtar and Wan Zurinah Wan Ngah. Tocotrienol-Rich Fraction, [6]-Gingerol and Epigallocatechin Gallate Inhibit Proliferation and Induce Apoptosis of Glioma Cancer Cells. (2014) Molecules, 19(9), 14528-14541.
  29. Hakim, L., Alias, E., Makpol, S., Ngah, W.Z.W., Morad, N.A., Yusof, Y.A.M. Gelam honey and ginger Potentiate the anti cancer effect of 5-FU against HCT 116 colorectal cancer cells (2014) Asian Pacific Journal of Cancer Prevention, 15 (11), pp. 4651-4657.
  30. Chin, K.-Y., Ima-Nirwana, S., Ibrahim, S., Mohamed, I.N., Ngah, W.Z.W. Vitamin D status in Malaysian men and its associated factors (2014) Nutrients, 6 (12), pp. 5419-5433.
  31. Chin Minning, Norfilza Mohd Mokhtar, Norlia Abdullah, Rohaizak Muhammad, Nor Aina Emran, Siti Aishah Md Ali, Roslan Harun and Rahman Jamal. Exploring breast carcinogenesis through integrative genomics and epigenomics analyses. (2014) International Journal of Oncology. 45: 1959-1968.
  32. Wong, Y.-L., Dali, A.Z.H.M., Mohamed Rose, I., Jamal, R., Mokhtar, N.M. Potential molecular signatures in epithelial ovarian cancer by genome wide expression profiling (2014) Asia-Pacific Journal of Clinical Oncology, . Article in Press.
  33. Norizam, S., Norfilza, M.M., Azmir, A., Nor Anita, M.M.N., Zaiton, Z. Circulating microRNA as biomarkers for young dyslipidemia men. (2014) Asian Pacific Journal of Tropical Disease, 4 (3), p. 235.
  34. Azmir, A., Norfilza, M.M., Norizam, S., Nor Anita, M.M.N., Zaiton, Z. Identification of circulating microRNAs in young men with central obesity. (2014) Asian Pacific Journal of Tropical Disease, 4 (3), p. 236.
  35. Nur Azurah, A.G., Wan Zainol, Z., Lim, P.S., Shafiee, M.N., Kampan, N., Mohsin, W.S., Mokhtar, N.M., Muhammad Yassin, M.A.J. Factors associated with placenta praevia in primigravidas and its pregnancy outcome. (2014) Scientific World Journal, 2014, art. no. 270120, .
  36. Mohamad Nasir Shafiee, Dahlia Abd Malik, Ryia Illani Mohd Yunos, William Atiomo, Mohd Hashim Omar, Nur Azurah Abdul Ghani, Ahmad Zailani Hatta, Claire Seedhouse, Caroline Chapman, and Norfilza Mohd Mokhtar. The effect of Metformin on endometrial tumor-regulatory genes and systemic metabolic parameters in polycystic ovarian syndrome – a proof-of-concept study. (2014) Gynecological Endocrinology, 2014, doi:10.3109/09513590.2014.989982
  37. Zhiqin W, Palaniappan S, Raja Ali RA. Inflammatory Bowel Disease-related Colorectal Cancer in the Asia-Pacific Region: Past, Present, and Future. (2014) Intestinal Res. Jul 2014; 12(3): 194–204.
  38. Sani N.A., Sapri H.F., Neoh H.M., Hussin S. First report on the molecular epidemiology of Malaysian Staphylococcus epidermidis isolated from a university teaching hospital. (2014) BMC Res Notes. 7:597. doi: 10.1186/1756-0500-7-597.
  39. Lee, L.-H., Zainal, N., Azman, A.-S., Ab Mutalib, N.-S., Hong, K., Chan, K.-G. Mumia flava gen. nov., sp. nov., an actinobacterium of the family Nocardioidaceae (2014) International Journal of Systematic and Evolutionary Microbiology, 64 (PART 5), pp. 1461-1467.
  40. Learn Han Lee, Nurullhudda Zainal, Adzzie-Shazleen Azman, Shu-Kee Eng, Goh Bey-Hing, Nurul-Syakima Ab Mutalib, Wai Fong Yin, and Kok Gan Chan. Diversity and antimicrobial activities of Actinobacteria isolated from tropical mangrove sediments in Malaysia. (2014) The Scientific World Journal.
  41. Learn-Han Lee, Nurullhudda Zainal, Adzzie-Shazleen Azman, Shu-Kee Eng, Nurul-Syakima Ab Mutalib, Wai-Fong Yin, and Kok-Gan Chan. Streptomyces pluripotens sp. nov., a bacteriocin-producingstreptomycete inhibiting methicillin-resistant Staphylococcus aureus. (2014) International Journal of Systematic and Evolutionary Microbiology. 64: 3297-3306.
  42. Learn-Han Lee, Adzzie-Shazleen Azman, Nurullhudda Zainal, Shu-Kee Eng, Nurul-Syakima Ab Mutalib, Wai-Fong Yin, and Kok-Gan Chan. Microbacterium mangrovi sp. nov., an amylolytic actinobacterium isolated from Tanjung Lumpur mangrove forest. (2014) International Journal of Systematic and Evolutionary Microbiology. 64: 3513-3519.
  43. Ab Mutalib Nurul-Syakima, Lee Learn-Han, Cheah Yoke-Kqueen. miR-205 in situ expression and localization of head and neck tumor tissue array. (2014) Asian Pacific Journal of Cancer Prevention. Vol. 15 (Accepted and In-Press)
  44. Abdullah, N., Attia, J., Oldmeadow, C., Scott, R.J., Holliday, E.G. The architecture of risk for type 2 diabetes: Understanding asia in the context of global findings. (2014) International Journal of Endocrinology, 2014, art. no. 593982.
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