UKM Medical Molecular Biology Institute

 Leading Institute in Molecular Medicine

– Publication 2018

  1. Buji RI, Abdul Murad NA, Chan LF, Maniam T, Mohd Shahrir MS, Rozita M, Shamsul AS, Mohamad Hussain R, Abdullah N, Jamal R, Nik Jaafar N. Suicidal ideation in systemic lupus erythematosus: NR2A gene polymorphism, clinical and psychosocial factors. 2018 apr;27(5):744-752. doi: 10.1177/0961203317742711.
  2. Nasir SN, Abu N, Ab Mutalib NS, Ishak M, Sagap I, Mazlan L, Rose IM, Jamal R. LOC285629 regulates cell proliferation and motility in colorectal cancer cells. Clin Transl Oncol. 2018 Jun;20(6):775-784. doi: 10.1007/s12094-017-1788-x.
  3. Borhanuddin B, Ahmad N, Shah SA, Murad NAA, Zakaria SZS, Kamaruddin MA, Jalal NA, Yusuf NAM, Patah AEA, Dauni A, Sallam WAFW, Jamal R. Association of job sectors with type 2 diabetes mellitus, hypercholesterolemia and obesity: a cross-sectional study from the Malaysian Cohort (TMC) project. Int Health. 2018 Sep 1;10(5):382-390. doi: 10.1093/inthealth/ihx075.
  4. Tan SC. Low penetrance genetic polymorphisms as potential biomarkers for colorectal cancer predisposition J Gene Med. 2018 Apr;20(4):e3010. doi: 10.1002/jgm.3010.
  5. Mohtar MA, Hernychova L, O’Neill JR, Lawrence ML, Murray E, Vojtesek B, Hupp TR. The sequence-specific peptide-binding activity of the protein sulfide isomerase AGR2 directs its’ stable binding to the oncogenic receptor EpCAM. Mol Cell Proteomics. 2018 Apr;17(4):737-763. doi: 10.1074/mcp.RA118.000573.
  6. Shahadin MS, Ab Mutalib NS, Latif MT, Greene CM, Hassan T. Challenges and future direction of molecular research in air pollution-related lung cancers. Lung Cancer. 2018 Apr;118:69-75. doi: 10.1016/j.lungcan.2018.01.016.
  7. Abu N, Zamberi NR, Yeap SK, Nordin N, Mohamad NE, Romli MF, Rasol NE, Subramani T, Ismail NH, Alitheen NB. Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia BMC Complement Altern Med. 2018 Jan 27;18(1):31. doi: 10.1186/s12906-018-2102-3.
  8. Abdullah N, Borhanuddin B, Patah AEA, Abdullah MS, Dauni A, Kamaruddin MA, Shah SA, Jamal R. Utilization of complementary alternative medicine in multiethnic population: the malaysian cohort study. J Evid Based Integr Med. 2018 Jan-Dec;23:2515690X18765945. doi: 10.1177/2515690X18765945.
  9. Tan SC, Ismail MP, Duski DR, Othman NH, Ankathil R. Prevalence and type distribution of human papillomavirus (HPV) in Malaysian women with and without cervical cancer: an updated estimate. Biosci Rep. 2018 Mar 29;38(2). pii: BSR20171268. doi: 10.1042/BSR20171268.
  10. Li X, Ooi FK, Tan SC, Zilfalil BA, ACE I/D and ACTN3 R577X genotypes, muscular and cardiovascular fitness in Malay males. Int J Pharm Bio Sci. 2018; 9(2):87-98. doi: 10.22376/ijpbs.2018.9.2.b87-98.
  11. Mohd Rani ZZ, Abdul Murad NA, Mian TS, Bernam AP, Abdullah A, Saimun S, Othman SN, Ali RA, Jamal R. HLA-B*15:02 screening in epileptic patients using a high resolution melting-real time PCR (HRM-QPCR). Neurology Asia 2018;23(2):137–144.
  12. Mohamad Yusof A, Jamal R, Muhammad R, Abdullah Suhaimi SN, Mohamed Rose I, Saidin S, Ab Mutalib NS. Integrated characterization of microRNA and mRNA transcriptome in papillary thyroid carcinoma. Front Endocrinol. 2018 Apr 16;9:158. doi: 10.3389/fendo.2018.00158.
  13. Abu N, Yeap SK, Nordin N, Tan SW, Ho WY, Alithe NB. Optimization of Illumina TruSeq targeted RNA expression (TREx) library qualitu. Sains Malaysiana. 2018;47(2):303-308. doi: 10.17576/jsm-2018-4702-12.
  14. Ser HL, Tan WS, Mutalib NA, Yin WF, Chan KG, Goh BH, Lee LH. Genome sequence of Streptomyces gilvigriseus MUSC 26T isolated from mangrove forest. Braz J Microbiol. 2018 Apr – Jun;49(2):207-209. doi: 10.1016/j.bjm.2017.04.012.
  15. Osman MA, Neoh H, Ab Mutalib NS, Chin SF, Jamal R. 16S rRNA Gene Sequencing for Deciphering the Colorectal Cancer Gut Microbiome: Current Protocols and Workflows. Front Microbiol. 2018 Apr 27;9:767. doi: 10.3389/fmicb.2018.00767.
  16. Abdullah N, Borhanuddin B, Shah SA, Hassan T, Jamal R. Global Lung Initiative 2012 spirometry reference values in a large Asian cohort of Malay, Chinese and Indian ancestry. Respirology. 2018 Dec;23(12):1173-1179. doi: 10.1111/resp.13330.
  17. Sulaiman SA, Abdul Murad NA, Mohamad Hanif EA, Abu N, Jamal R. Prospective advances in circular RNA investigation. Adv Exp Med Biol. 2018;1087:357-370. doi: 10.1007/978-981-13-1426-1_28.
  18. Letchumanan V, Ser HL, Tan WS, Ab Mutalib NS, Goh BH, Chan KG, Lee LH. Book Title: Game Changer-Next Generation Sequencing and its Impact on Food Microbiology. CHAPTER 1 – Genome Sequence of Vibrio parahaemolyticus VP152 Strain Isolated from Penaeus indicus in Malaysia. Frontiers in Microbiology. 2018; 9:158.
  19. Letchumanan V, Chan KG, Khan TM, Bukhari SI, Ab Mutalib NS, Goh BH, Lee LH. Book Title: Vibrionaceae Diversity, Multidrug Resistance and Management. CHAPTER 1 – Bile Sensing: The Activation of Vibrio parahaemolyticus Frontiers in Microbiology. 2018;1:62-67.
  20. Mohd Nawawi N, Selveindran NM, Rasat R, Chow YP, Abdul Latiff Z, Syed Zakaria SZ, Jamal R, Abdul Murad NA, Abd Aziz BB. Genotype-phenotype correlation among Malaysian patients with osteogenesis imperfecta. Clinica Chimica Acta. 2018 Sep;484:141-147. doi: 10.1016/j.cca.2018.05.048.
  21. Rodrigues P, Patel SA, Harewood L, Olan I, Vojtasova E, Syafruddin SE, Zaini MN, Richardson EK, Burge J, Warren AY, Stewart GD, Saeb-Parsy K, Samarajiwa SA, Vanharanta S. NF-κB–Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discovery. 2018 Jul;8(7):850-865. doi: 10.1158/2159-8290.CD-17-1211.
  22. Chin SF, Osman J, Jamal R. Simultaneous determination of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 in human serum by ultra performance liquid chromatography: An economical and validated method with bovine serum albumin. Clinica Chimica Acta. 2018 Oct;485:60-66. doi: 10.1016/j.cca.2018.06.024.
  23. Suhaimi SS, Ab Mutalib NS, Khor SS, Md Zain RR, Syafruddin SE, Abu, Mohd Dali AZH, Jamal R. Targeted next generation sequencing identifies actionable targets in oestrogen receptor positive and oestrogen receptor negative endometriod endometrial cancer. Frontiers in Pharmacology. 2018 Jul 13;9:750. doi: 10.3389/fphar.2018.00750.
  24. Gerlach JP, Jordens I, Tauriello DVF, Land-Kuper IV, Bugter JM, Noordstra I, van der Kooij J, Low TY, Pimentel-Muiños FX, Xanthakis D, Fenderico N, Rabouille C, Heck AJR, Egan DA, Maurice MM. TMEM59 potentiates Wnt signaling by promoting signalosome formation. 2018 Apr 24;115(17):E3996-E4005. doi: 10.1073/pnas.1721321115.
  25. Magliozzi R, Carrero ZI, Low TY, Yuniati L, Valdes-Quezada C, Kruiswijk F, van Wijk K, Heck AJR, Jackson CL Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1. Cell Reports. 2018 Jun 12;23(11):3381-3391.e4. doi: 10.1016/j.celrep.2018.05.031.
  26. Lee PY, Chin SF, Low TY, Jamal R. Probing the colorectal cancer proteome for biomarkers – current status and perspectives. Journal of Proteomics. 2018 Sep 15;187:93-105. doi: 10.1016/j.jprot.2018.06.014.
  27. Ahmad N, Jamal R, Shah SA, Gafor AHA, Murad NAA. Renin-angiotensin-aldosterone-system gene polymorphisms and type 2 diabetic nephropathy in Asian populations: an updated meta-analysis. Current Diabetes Review. 2018 Jul 8. doi: 10.2174/1573399814666180709100411.
  28. Hon KW, Abu N, Ab Mutalib NS, Jamal R. miRNAs and lncRNAs as Predictive Biomarkers of Response to FOLFOX Therapy in Colorectal Cancer. Frontiers in Pharmacology. 2018 Aug 6;9:846. doi: 10.3389/fphar.2018.00846.
  29. Chin SF, Megat Mohd Azlan PIH, Mazlan L, Neoh HM. Identification of Schizosaccharomyces pombe in the guts of healthy individuals and patients with colorectal cancer: preliminary evidence from a gut microbiome secretome study. Gut Pathogens. 2018 Jul 10;10:29. doi: 10.1186/s13099-018-0258-5.
  30. Woon YL, Hor CP, Lee KY, Mohd Anuar SFZ, Mudin RN, Sheikh Ahmad MK, Komari S, Amin F, Jamal R, Chen WS, Goh PP, Yeap L, Lim ZR, Lim TO. Estimating Dengue Incidence and Hospitalization in Malaysia, 2001 to 2013. BMC Public Health. 2018 Aug 2;18(1):946. doi: 10.1186/s12889-018-5849-z.
  31. Apidi E, Wan Taib WR, Hassan R, Ab Mutalib NS, Ismail I. A review on effect of genetic features on treatment responses in acute myeloid leukemia. Meta Gene. 2018;18:31-38. doi: 10.1016/j.mgene.2018.07.012.
  32. Borhanuddin B, Mohd Nawi A, Azhar Shah S, Abdullah N, Syed Zakaria SZ, Kamaruddin MA, Velu CS, Ismail N, Abdullah MS, Kamat SA, Awang A, Hamid MA, Jamal R. 10-Year Cardiovascular Disease Risk Estimation Based on Lipid Profile-Based and BMI-Based Framingham Risk Scores Across Multiple Sociodemographic Characteristics: The Malaysian Cohort (TMC) Project. The Scientific World Journal. 2018; 2018: 2979206. doi: 10.1155/2018/2979206.
  33. Chi Soh JE, Abu N, Jamal R. Potential Immune-eliciting Cancer Testis Antigens (CTAs) in Colorectal Cancer. Immunotherapy. 2018 Sep;10(12):1093-1104. doi: 10.2217/imt-2018-0044.
  34. Zahari M, Sulaiman SA, Othman Z, Ayob Y, Karim FA, Jamal R. Mutation spectrum of F8 and F9 in a cohort of Hemophilia A and Hemophilia B patients in multi-ethnic Malaysian population. The Mediterranean Journal of Hematology and Infectious Diseases. 2018 Sep 1;10(1):e2018056. doi: 10.4084/MJHID.2018.056.
  35. Abu N, Hon KW, Jeyamaran S, Jamal R. Long non coding RNAs as Biotargets in Cisplatin Resistant Cancers. Future Oncology. 2018 Nov 23. doi: 10.2217/fon-2018-0303.
  36. Antonova S, Haffke M, Corradini E, Mikuciunas M, Low TY, Signor L, van Es RM, Scheer E, Vos HR, Gupta K, Tora L, Heck AJR, Timmers HTM, Berger I. Chaperonin CCT Checkpoint Function in Basal Transcription Factor TFIID Assembly. Nature Structural & Molecular Biology. 2018 Dec;25(12):1119-1127. doi: 10.1038/s41594-018-0156-z.
  37. Lee LH, Ab Mutalib NS, Law JW, Wong SH, Letchumanan V. Discovery on antibiotic resistance patterns of Vibrio parahaemolyticus in Selangor reveals carbapenemase producing Vibrio parahaemolyticus in marine and freshwater fish. Frontiers in Microbiology. 2018 Oct 25;9:2513. doi: 10.3389/fmicb.2018.02513.
  38. Razak SAA, Murad NAA, Masra F, Chong DLS, Abdullah N, Jalil N, Alauddin H, Sabudin RZAR, Ithnin A, Alias H, Khai LC, Aziz NA, Muda Z, Ibrahim H, Jamal R, Latif ZA. Genetic Modifiers of Fetal Haemoglobin (HbF) and Phenotypic Severity in β-Thalassemia Patients. Current Molecular Medicine. 2018;18(5):295-305. doi: 10.2174/1566524018666181004121604.
  39. Low TY, Ang MY, Mohtar A, Jamal R. Connecting Proteomics to NGS: Proteogenomics and its Current Applications in Biology. Proteomics. 2018 Nov 15:e1800235. doi: 10.1002/pmic.201800235.
  40. Ser HL, Tan WS, Mutalib NA, Yin WF, Chan KG, Goh BH, Lee LH. Genome sequence of Streptomyces gilvigriseus MUSC 26T isolated from mangrove forest. (2018) Progress in Microbiology and Molecular Biology, 1, 1-3.
  41. Ser HL, Yin WF, Chan KG, Mutalib NA, Lee LH. Genome sequence of Novosphingobium malaysiense strain MUSC 273T, novel alpha-pro-teobacterium isolated from intertidal soil (2018) Progress in Microbiology and Molecular Biology, 1, 1-2.
  42. Ser HL, Chan KG, Tan WS, Yin WF, Goh BH, Mutalib NA, Lee LH Complete genome of mangrove-derived anti-MRSA streptomycete, Streptomyces pluripotens MUSC 135T (2018) Progress in Microbiology and Molecular Biology, 1, 1-4.
  43. Zaini MN, Patel SA, Syafruddin SE, Rodrigues P, Vanharanta S. Endogenous HIF2A reporter systems for high-throughput functional screening. Scientific Reports. 2018 Aug 13;8(1):12063. doi: 10.1038/s41598-018-30499-2.
  44. Abdullah N, Murad NAA, Attia J, Oldmeadow C, Kamaruddin MA, Jalal NA, Ismail N, Jamal R, Scott RJ, Holliday EG. Differing Contributions of Classical Risk Factors to Type 2 Diabetes in Multi-Ethnic Malaysian Populations. Int J Environ Res Public Health. 2018 Dec 10;15(12). pii: E2813. doi: 10.3390/ijerph15122813.
  45. Megat Mohd Azlan PI, Chin SF, Low TY, Hui-Min N, Jamal R. Analysing the Secretome of Gut Microbiota as the Next Strategy For Early Detection of Colorectal Cancer. Proteomics. 2018 Dec 17:e1800176. doi: 10.1002/pmic.201800176.
  46. Letchumanan V, Wong PC, Goh BH, Ming LC, Pusparajah P, Wong S, Ab Mutalib NS, Lee LH. A Review on the Characteristics, Taxanomy and Prevalence of Listeria Monocytogenes. Progress in Microbiology and Molecular Biology. 2018;1:1-8.
  47. Ab Mutalib NS, Baharuddin R, Jamal R. Chapter 21 Epigenome-wide analysis of DNA methylation in colorectal cancer. Computational Epigenetics and Diseases (Accepted).
  48. Ab Mutalib NS, Sulaiman SA, Jamal R. Chapter 6 Computational tools for microRNA target prediction cancer. Computational Epigenetics and Diseases (Accepted).
  49. Ibrahim K, Abdullahi AD, Abdul Murad NA, Harun R, Jamal R. In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking. Asia-Pacific Journal of Molecular Medicine (Accepted).
  50. Abu N, Ab Mutalib NS, Jamal R. Gene Expression Analysis of the concomitant existence of LVI and PNI in CRC patients. Asia-Pacific Journal of Molecular Medicine (Accepted).
  51. Tee LF, Tan TL, Neoh HM, Jamal R. Rapid Detection of Sepsis using CESDA: the Caenorabditis elegans Sepsis Detection Assay. Journal of the Brazillian Society of Tropical Medicine (Accepted).
  52. Lee PY, Low TY, Jamal R. Probing the endogenous peptidomes of cancer for biomarkers – a new endeavor. Advances in Clinical Chemistry. (Accepted).
  53. Sulaiman SA, Abdul Murad NA, Chow YP, Mohd Rani ZZ, A. Aziz DA, Azhari H, Syed Omar SA, Abdul Latiff Zarina, Jamal R. Mutations in KIF27, GNAS and IFT140 genes in a patient with VACTERL association. Asia-Pacific Journal of Molecular Medicine (Accepted).
  54. Mohd Hanif EA. Overview on Epigenetic Reprogramming: A Potential Therapeutic Intervention in Triple Negative Breast Cancers. Asian Pacific Journal of Cancer Prevention (Accepted).
  55. Mohammed Nawi A, Chin SF, Jamal R, Tissue and Serum Trace Elements Concentration Among Colorectal Patients: A Systematic Review of Case Control Studies. Iran J Public Health (Accepted).
  56. Chow YP, Mohd Yunos RI, Mohd Rose I, Abdullah N, Muhammad R, Abdullah Suhaimi SN, Jasmin SJ, Mahamad Nadzir N, Ab Mutalib NS, Jamal R. Exome Sequencing Uncovers Targeting PI3K/MAPK/NF-kβ Pathways as a Rational Therapeutic Strategy for Malaysian Luminal Breast Cancer. Progress in Microbiology and Molecular Biology. (Accepted)
  57. Johdi NA, Jamal R. Emerging soluble protein markers in colorectal cancer. Journal of Biochemistry, Microbiology and Biotechnology. (Accepted).
  58. Nordin N, Yeap SK, Rahman HS, Zamberi NR, Abu N, Mohamad NE, How CW, Masarudin MJ, Abdullah R, Alitheen NB. In vitro cytotoxicity and anticancer effects of citral nanostructured lipid 2 carrier on MDA MBA-231 human breast cancer cells. Scientific Reports (Accepted).
  59. Abd Razak N, Abu N, Ho WY, Zamberi NR, Tan SE, Alitheen NB, Long K, Yeap SK. Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via 2 cell cycle arrest, anti-angiogenesis and induction of apoptosis. Scientific Reports (Accepted).
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