Know Your Medicine : Orlistat for overweight problem 31



-Available in capsules.

-Accompanied by a low calorie diet and exercise in order to maximize the effect of weight loss and maintain the outcome.


How This Medicine Works?

-Orlistat is categorized as a type of lipase inhibitor.

-It works by preventing a portion of dietary fats from being absorbed into the intestines.

-The unabsorbed fat is then removed from the body in the stool.


When to take?

·         Orlistat should be taken with fat-containing meal (during or up to  1 hour after the meal).

·         One tablet is taken during each meal.

·         Omit dose if meal is occasionally missed or contains no fat.


While Using This Medicine:

-Follow the diet plan given by doctor.

-If orlistat is taken with a diet that contains high level of fat (a diet containing more than 30% of the total daily calories from fat), or with any meal that is rich in fat, you are more likely to experience side effects from the medication.

-Orlistat blocks human body’s absorption of some fat-soluble vitamins and beta carotene.

-Therefore, when you use orlistat you should take a daily multivitamin that contains vitamins A, D, E, K, and beta-carotene.

-Take the multivitamin once per day, 2 hours before or after taking orlistat, during bedtime or as suggested by physicians.



What are the side effects?

-All medicines may have some unnecessary side effects.

-It can be severe in certain conditions, but mostly they are mild.

-Tell your doctor or pharmacist if you experience any side effects which are severe or persistent.

-Possible side effects:

  • changes in bowel movement habits
  • oily spotting on underwear or on clothing
  • loose, oily or fatty stool
  • pain or discomfort in the rectum (bottom)
  • stomach pain
  • irregular menstrual periods
  • headache
  • anxiety
  • rash
  • nausea or vomiting
  • difficulty in breathing or swallowing
  • excessive tiredness


Storage and disposal:

·         Store at room temperature and in a dry place.

·         Keep away from direct sunlight.

·         Keep out of reach of children.

·         Do not use after the expiry date.

·         Return any unused or expired medication to the nearest pharmacy.




Below are the summary of information of orlistat in picture form.





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